Principal Scientist Cmc Analytics
vor 2 Wochen
Our client is biotech company specialized in the development of glycoengineered biologics near Zurich.
Tasks
- Based on the analytical control strategy define in/ outsourcing concepts between CRO's and CMO's
- Ensure capacity sourcing to reach goals according to plans
- Planning and execution of early formulation and stability studies based on established stability indicating assays
- Phase appropriate validation of analytical methods
- Analyzing biomolecules such as proteins and glycans (e.g., by U/HPLC, SEC, IEX, mass spectrometry, immunoassays)
- Technology transfer to and oversight of CMOs and CROs tasked with analysis of molecules for product characterization and GMP release testing
- Independently planning and executing analytical research projects
- Maintaining analytical instruments
- Processing, evaluating, and reporting of data as well as presentation in scientific meetings
Requirements:
- PhD in Natural Sciences or Analytical Sciences
- 10+ years 'working experience in the biotech and/or pharma industry
- Minimum 5 years of relevant analytical/ QC industry experience with GMP exposure
- Broad Experience and knowledge in protein biochemistry and protein analytics, including post translational modifications such as glycosylation
- Handson experience in analytical method validation, technology transfer and CMC regulatory analytical matters
- Proven experience in chromatographic analysis of biological molecules including proteins and peptides is a must
- Practical experience with mass spectrometry and data evaluation
- Handson experience working with and maintaining HPLC/UPLC instruments
- Experience in statistical data evaluation and high affinity for software tools
- Wellconnected in the analytical technology and instrumentation community
- Good ITknowledge (Excel, PowerPoint, databases)
- Very good communication skills in English, written and verbal
- Excellent planning and strong organizational skills, able to manage multiple tasks simultaneously and set priorities
- Proactive and problemsolving attitude
- Personal resilience, perseverance, energy and drive
- Excellent conceptual and scientific thinking to approach and solve complex issues and their implications
- Selfmotivation and ability to work independently in a fastpace, small company environment
- Excellent interpersonal and negotiation skills
- Team player, collaborative attitude.
Benefits:
- Startup culture
- 5 weeks vacation
- career opportunities
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