Aktuelle Jobs im Zusammenhang mit Phd Student Position to Study Effects of The - Bern, Bern - Universität Bern Universität Bern
-
PhD Position in Climate Extremes and Health
vor 2 Wochen
Bern, Bern, Schweiz Universität Bern VollzeitResearch Opportunity at Universität BernThe Institute of Geography at Universität Bern invites applications for a PhD position in the field of climate extremes and health. This research project is part of a Horizon Europe project on climate change adaptation in Europe.Project OverviewThe PhD project aims to develop and analyze health-relevant heat...
-
Bern, Bern, Schweiz Universität Bern VollzeitResearcher in Clinical Epidemiology and Substance UseThe Institute of Primary Health Care at the University of Bern is seeking a highly motivated PhD student to join our research team. As a researcher in clinical epidemiology and substance use, you will contribute to the ongoing Efficacy, Safety and Toxicology of ENDS (ESTxENDS) randomized controlled trial,...
-
PhD Position in Biomedical Research
Vor 2 Tagen
Bern, Bern, Schweiz Kanton Bern VollzeitPhD Position in Biomedical SciencesAt the University Institute of Diagnostic, Interventional and Paediatric Radiology, Experimental Radiology Laboratory, we are offering a unique PhD opportunity to a talented and highly motivated student. The successful candidate will have the chance to investigate interactions between metallopharmaceuticals and cells using...
-
Bern, Bern, Schweiz Universität Bern VollzeitResearch Opportunity at Universität BernThe Institute of Primary Health Care at Universität Bern is seeking a highly motivated PhD student to join our research team. As a PhD student, you will work under the guidance of Prof. Dr. med. Reto Auer and contribute to the ongoing Efficacy, Safety and Toxicology of ENDS (ESTxENDS) randomized controlled...
-
Bern, Bern, Schweiz Universität Bern VollzeitJob Opportunity at Universität BernWe are seeking a highly motivated PhD Student in Clinical Substance Use Epidemiology to join our research team at the Institute of Primary Health Care. The successful candidate will work under the guidance of Prof. Dr. med. Reto Auer and contribute to the ongoing Efficacy, Safety and Toxicology of ENDS (ESTxENDS)...
-
PhD Position in Islamic Studies
Vor 6 Tagen
Bern, Bern, Schweiz Universität Bern VollzeitPhD Student in Islamic/Middle Eastern StudiesThe Department of Social Anthropology and Cultural Studies (SACS) at the University of Bern is seeking a highly motivated PhD student to join the unit "Middle East and Muslim Societies," within Prof. Dr Serena Tolino's research team.Project OverviewThe TraIL project aims to provide cutting-edge research on the...
-
PhD Position in Macroeconomic Research
vor 2 Wochen
Bern, Bern, Schweiz Universität Bern Vollzeit**About the Position**Universität Bern is seeking a highly qualified researcher to join our Macroeconomics group. As a PhD candidate, you will engage in research and teaching activities, focusing on projects related to Monetary Economics and Empirical Macroeconomics.**Key Responsibilities**Participate in the Swiss Program for Beginning Doctoral Students in...
-
Logic and Theory Group PhD Researcher
vor 2 Wochen
Bern, Bern, Schweiz Universität Bern Vollzeit**Project Overview**We are seeking two PhD students to join our research project on Epistemic Group Attitudes in the Logic and Theory Group of the Institute of Computer Science at the University of Bern.**Research Focus**The project aims to develop and investigate new notions of group knowledge in multi-agent systems. We will devise novel variants of common...
-
PhD Researcher in Childhood Cancer Epidemiology
vor 2 Wochen
Bern, Bern, Schweiz Universität Bern VollzeitJob Opportunity at Universität BernAbout the PositionWe are seeking a highly motivated and skilled PhD researcher to join our team at the Institute of Social and Preventive Medicine (ISPM) of Universität Bern. The successful candidate will be part of a dynamic and multidisciplinary team conducting research in the field of child health and...
-
PhD Position in Art History
Vor 5 Tagen
Bern, Bern, Schweiz Universität Bern VollzeitPhD Position in Art HistoryThe Universität Bern is seeking a highly motivated PhD candidate to join the research project "Artistic Failures in Renaissance Ceramic Workshops". This project aims to analyze ceramic workshops in Central Europe during the sixteenth century, focusing on the role of failure in the creative process.Project OverviewThe project will...
-
PhD Position in Metabolic Physiology
Vor 2 Tagen
Bern, Bern, Schweiz Universität Bern VollzeitPhD Position in Metabolic PhysiologyWe are seeking a highly motivated and ambitious PhD candidate to join our research group at the University of Bern and University Hospital Bern, Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism (UDEM). The successful candidate will have the opportunity to work on a cutting-edge project addressing...
-
Bern, Bern, Schweiz Universität Bern VollzeitJob DescriptionWe are seeking a highly motivated and qualified PhD student to join our research team at the Universität Bern, Department of Social Anthropology and Cultural Studies (SACS). The successful candidate will be part of the TraIL project, a research initiative focused on the legal history of labour in Islamicate societies.Project OverviewThe TraIL...
-
Scientist in Environmental Health and Climate Change
vor 2 Wochen
Bern, Bern, Schweiz Universität Bern VollzeitResearch Opportunity at Universität BernThe Institute of Geography at Universität Bern invites applications for a PhD position in the field of climate extremes and health. This research project is part of a Horizon Europe project on climate change adaptation in Europe.Project OverviewThe PhD project aims to develop and analyze health-relevant heat...
-
Researcher in Heat-Related Health Impacts
vor 2 Wochen
Bern, Bern, Schweiz Universität Bern VollzeitResearch Opportunity at Universität BernThe Institute of Geography at Universität Bern invites applications for a PhD position in the field of climate extremes and health. This research project is part of a Horizon Europe project on climate change adaptation in Europe.Project OverviewThe PhD project aims to develop and analyze health-relevant heat...
-
Biomedical Research Scientist Position
vor 2 Wochen
Bern, Bern, Schweiz Kanton Bern VollzeitJob Opportunity in Biomedical ResearchAt Kanton Bern, we are offering a unique opportunity for a talented and highly motivated researcher to join our team in the Experimental Radiology Laboratory.The ChallengeWe are seeking a researcher with a strong background in cell biology, biology, chemistry, biochemistry, biomedicine, or pharmacy to investigate...
-
PhD Position in Molecular Cell Biology Researcher
vor 2 Wochen
Bern, Bern, Schweiz Universität Bern VollzeitJob Opportunity at Universität BernWe are seeking a highly motivated PhD student to join our research team at the Institute of Cell Biology, Universität Bern. The successful candidate will have the opportunity to work on a cutting-edge project focused on the molecular mechanisms of mitochondrial transcription in Trypanosoma brucei.Research ProjectThe...
-
PhD Position in Art History
vor 2 Wochen
Bern, Bern, Schweiz Universität Bern VollzeitAbout the ProjectThe AFIRE project aims to integrate failed experiments and non-linear processes of artmaking into the history of European art. The project will analyze ceramic workshops that operated in different parts of Central Europe during the sixteenth century to highlight the interconnectedness of the region.Research FocusThe PhD Candidate will work...
-
Bern, Bern, Schweiz Universität Bern VollzeitResearch Position in Paediatric Respiratory MedicineThe Institute of Social and Preventive Medicine at the University of Bern is seeking a highly motivated research fellow to join our team in Paediatric Respiratory Medicine. As a member of our Child and Adolescent Health Group, you will contribute to the Swiss Paediatric Airway Cohort (SPAC) study, a large...
-
Academic Position in Precision Oncology
Vor 6 Tagen
Bern, Bern, Schweiz Medizinisches Dekanat Uni. Bern VollzeitJob Opportunity in Precision OncologyWe are seeking a highly qualified individual to fill an open rank academic position in Precision Oncology. The successful candidate will contribute to our research and teaching efforts in this exciting field.Key Responsibilities:Conduct innovative research in Precision OncologyTeach and mentor students in related...
-
Bern, Bern, Schweiz Universität Bern VollzeitPhD Position in Metabolic Physiology for Women's HealthWe are seeking a highly motivated and ambitious PhD candidate to join our research group at the University of Bern and University Hospital Bern, Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism (UDEM). The successful candidate will have the opportunity to contribute to an...
Phd Student Position to Study Effects of The
vor 3 Monaten
PhD student position to study effects of the neurite outgrowth inhibitor NogoA in neurodegeneration:
A PhD student position is available at the University of Bern, Switzerland, to join the research group of Meike Mevissen (Vet. Pharmacology & Toxicology).
A leading area of pharmaceutical research is based on neuroscience therapeutics with vast resources applied to the discovery and development of drugs for disorders in the central nervous system (CNS).
According to the World Health Organization (WHO), 8 out of 10 disorders in the 3 highest disability classes are neurological problems and they account for about 12% of deaths worldwide.
Parkinson's disease (PD) is a multifactorial neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra.Despite the severity of the disease and the rapidly increasing prevalence of PD, the pathogenesis of PD is not sufficiently understood, the therapy is mostly symptomatic, and there are no treatments to cure the disease or slow down the progression of the neurodegeneration.
It is therefore crucial to better define the mechanisms leading to the disease and identify targets for therapeutical intervention.
The neurite growth inhibitor A (NogoA) was found to co-localize with dopaminergic neurons in the substantia nigra (SNpc) of the brain.
Antagonization of NogoA was shown to increase survival of transplanted human dopaminergic neurons in a PD rat model, suggesting a role of NogoA in PD.
Based on these findings, we therefore created NogoA-deficient (RTN4-KO) cells. The RTN4-KO clone showed a significant reduction of α-synuclein and a visual tendency of more dopaminergic neurons.In this project, we will address the effects of NogoA during neuronal development and neurodegeneration using unique 2D and 3D models that we have established.
These analyses will be complemented by the quantitative assessment of key players in cellular pathways involved in neuronal differentiation and degeneration and mitochondrial function.
In the scope of this PhD position, we intend to use a variety of advanced models and biochemical, genetic, state-of-the-art microscopy technologies of stem cell
- and neuronal-markers combined with high-content analysis, and functional approaches to understand the impact of the neurite growth inhibitors NogoA in neuronal development and neurodegeneration. To this purpose, we use various model systems, including wild-type and disease models, and CRISPR-Cas9-created NogoA-deficient 2D cell lines and 3D midbrain organoids suitable for investigating the effects of NogoA in neuronal development and neurodegeneration.
We offer a young and enthusiastic research group, state-of-the art research facilities at the attractive working location in Bern. The remuneration is in accordance with the Swiss National Science Foundation (SNSF) regulations (annual brutto salary of CHF 47, ,040).
This position is a 3-4 year appointment and is available from September 1st, 2023 onwards.
