Postdoc to Investigate The Inactivation of Viruses

vor 1 Woche

Lausanne, Waadt, Schweiz EPFL Vollzeit

EPFL, the Swiss Federal Institute of Technology in Lausanne, is one of the most dynamic university campuses in Europe and ranks among the top 20 universities worldwide.

The EPFL employs more than 6,000 people supporting the three main missions of the institutions:
education, research and innovation.

The EPFL campus offers an exceptional working environment at the heart of a community of more than 16,000 people, including over 12,000 students and 4,000 researchers from more than 120 different countries.


Postdoc to investigate the inactivation of viruses by bacterial communities:

Your mission:

Our group is interested in the fate of human viruses in the environment.

Viruses enter natural water bodies via the discharge of wastewater, from where they can be transmitted to new hosts and cause a range of diseases from diarrhea to hepatitis and meningitis.

The probability that a virus will encounter and infect a new host depends in part on its ability to persist in the environment.

Yet, our understanding of the environmental fate of human viruses is far from complete. A significant blind spot is the role of microorganisms in reducing virus persistence.

It is known that viruses are more rapidly inactivated in biologically active samples, though the underlying mechanisms are not understood.


Main duties and responsibilities include:


The objective of this project is to characterize the role of enzymes produced by freshwater bacterial communities in virus inactivation.

We will use chemostat experiments to cultivate microbial populations of different diversities, characterize the enzyme pool the produce, and investigate its ability to degrade viral capsids and cause inactivation.

For this work, we will combine virus inactivation studies with metagenomics and -transcriptomics, as well as enzyme assays.

Your profile:

We offer:


We offer a fully funded position in stimulating international research environment, good research infrastructures and resources, a competitive salary, and the opportunity to live and work along the shores of beautiful Lake Geneva.


Start date:

September 2023 or upon agreement.

Term of employment:

Fixed-term (CDD)

Work rate:

100%

Duration:

Up to 4 years

Contact:

To apply, please send the following documents

as a single pdf file to
- a letter of motivation
- your CV including publication list
- university transcripts
- the name and contact information of at least two references

Reference:

Job Nb 2900

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