in Vitro Assay Development Research Assistant

vor 2 Wochen

Genf, Genf, Schweiz Neurosterix Vollzeit

_At Neurosterix, we aspire to be the '_
world leader in allosteric modulators for the treatment of neurological disorders'_ _and we are looking for a hands-on Research Assistant/Technician, to help us achieve it.

_

Job Mission

Description of the Work
- browse the literature, build knowledge around the therapeutic target of interest
- plan experimental concepts & implement them
- design fusion proteins, suitable for cellular signaling using FRET/BRET approaches
- generate mammalian cell lines expressing the assay system
- experimentally characterize binding, and biological activity of allosteric modulators
- analyze & document results, provide pharmacological interpretations
- prepare presentations, suggest follow-up experiments
- use software tools to analyze mode of action of our compounds on a molecular level
- supervise the work of interns in our team

Required skills

  • Masters' degree (or equivalent), in Molecular and Cellular Biology, Biochemistry, Pharmacology, Neuroscience, Live Science Engineering, or in a related field
- demonstrated previous experience (1-2 years) in assay development, receptor pharmacology, cellular signaling
- experience in using software packages to model and interpret complex data will be considered an asset
- experience in general cell-culture techniques and DNA engineering
- knowledge of molecular and cell biology, biochemistry, biophysics, organic chemistry
- high degree of independence, eagerness to take on an own project.
- proactive mindset, combined with excellent communication, reporting and documentation skills
- attention to detail, and flexibility are essential
- ability to work efficiently and flexibly in a small team.
- basic IT: Microsoft Office. GraphPad, Pymol, etc... is a plus
- good working knowledge of English and/or French

  • Swiss Nationality or eligible for Swiss work permit

Job Type: 100%

Schedule:

  • 8 Hour Shift

Work Location:
In person

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