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Digital Biomarker Scientific Solutions Manager

vor 7 Monaten


Basel, Schweiz Roche Vollzeit

The Position

Job Mission

We, the Digital Biomarker (dBM) Chapter in Roche Information Solutions, are an integrated team of scientists, technologists, data analysts and operationalization experts, that leverages mobile technologies like smartphones and wearables to collect objective and continuous sensor data from patients in clinical trials. 

We co-create innovative digital remote monitoring concepts for sensitive and meaningful drug development endpoints, implement them in technology solutions, develop health related outcome measures with the data, seek community- and regulatory acceptance of corresponding endpoints and offer them to Biopharma companies and research institutes for use in clinical trials. Moreover, we are establishing the scientific foundations for disease monitoring and screening solutions in clinical practice.

You will be responsible to … 

Partner with a broad stakeholder community of patients, care givers, physician and other experts to create digital health solutions 

Act as scientific product owner for a set of digital biomarker solutions for Roche and external customers with needs in areas of Disease understanding / Drug portfolio decision-making (phase I-II) / Regulatory treatment approval (phase III-IV) / Clinical trial participant selection / Clinical care

Identify and develop scientific concepts to address the unmet measurement needs

Oversee end2end scientific product development

Lead large interdisciplinary project teams that develop and implement the scientific digital biomarker solutions 

Drive the drug development tool regulatory strategy for digital endpoint endorsement and qualification

Drive scientific community acceptance of digital measures and maintain a strong network of collaborators spanning industry and academia

Develop scientific core messages for product marketing

Support interactions with customers during the pre- and post-sales phases 

Represent RIS scientifically in pre-sales conversations on RIS Digital Biomarker products

Co-author high-profile scientific publications and posters

Represent Roche at relevant high-profile conferences

Establish yourself as a respected scientific digital biomarker expert and advocate in the research and development community at Roche and externally through cross-industry task forces, communicating results at conferences and in peer-reviewed publications.

Your profile: 

University degree or equivalent) in Life Sciences or related field with a minimum of 10 years related experience in the pharmaceutical and digital health industry 

Track record of writing compelling publications in high impact, peer reviewed journals

Proven experience with senior stakeholder management and external collaborations

Deep scientific product management experience in a large Pharma or Medtech company 

Deep experience in the area of sensor data and digital biomarker development

Provable experience leading in matrix setup, recognized for embracing new ways of leading and working, with strengths in coaching and fostering a collaborative environment

Transparent communicator and able to apply effective empowering leadership

Previous clinical experience in Neuroscience (especially Parkinson’s Disease, Huntington’s Disease, Multiple Sclerosis)

Should you have these additional nice-to-have skills, you are the ideal team member we are searching for:

Hands-on work with sensor or other high frequency/complex time series data, including feature engineering

Experience with developing digital biomarkers, digital clinical outcomes and digital endpoints

FDA/EMA regulatory interactions or regulatory consortias regarding clinical drug development and novel drug development endpoints

Deep experience with software project ownership, and especially with functional requirement models like use case and user story development, and requirement gathering

Experience with engineering hardware for remote patient monitoring and sensor data collection