Research Associate, Experimental Immunology

vor 4 Wochen


Basel, Schweiz BIIE Vollzeit

Research Associate
The Botnar Institute of Immune Engineering (BIIE) is a non-profit research institute focusing on developing translational solutions for treatment, prevention and diagnostics of diseases relevant in global child & adolescent health. We are seeking a candidate with a solid background in molecular biology and experimental immunology, with hands-on experience in flow cytometry, sequencing library preparation or monoclonal antibody production.

Tasks

The key responsibilities of the Research Associate:

  • Design and optimize spectral flow cytometry panels for isolating and studying immune cells
  • Develop and optimize protocols for single-cell and bulk immune receptor repertoire sequencing
  • Prepare the NGS library and analyze the sequencing data.
  • Produce and characterize monoclonal antibodies using biochemical and biophysical methods.
  • Collaborate with cross-functional teams to establish and optimize automation
  • Analyze and interpret experimental data, maintaining detailed records of experiments and outcomes.
  • Contribute to the development of new technologies and methodologies to improve high-throughput protein expression workflows.
  • Prepare technical reports, summaries, protocols, and quantitative analyses.
  • Present findings to team members and contribute to scientific discussions within the group.
Requirements

Core skills and experience expected from the Research Associate:

  • Bachelor’s or Master’s degree in Molecular Biology, Biochemistry, Chemical Engineering, or related field.
  • Experience with flow cytometry and cell sorting
  • Familiarity with molecular biology techniques, such as PCR, cloning, and vector construction.
  • Experience in monoclonal antibody production protein expression, purification, and characterization.
  • Strong organizational skills with the ability to manage multiple projects simultaneously.
  • Excellent problem-solving abilities and attention to detail.
  • Effective communication skills, both written and verbal.
  • Ability to work both independently and collaboratively in a team-oriented environment.

About the Botnar Institute of Immune Engineering

The Botnar Institute of Immune Engineering (BIIE) is a newly founded non-profit research organization aiming to become a world leading research institute for the advanced study of immunological systems with a mission to develop translational solutions for the diagnosis, treatment and prevention of disease. The scientific foundation of the BIIE and the broader field of Immune Engineering is based on the intersection of three interdisciplinary subdomains: (i) systems immunology, (ii) synthetic immunology and (iii) computational immunology. The BIIE will serve as a hub for multidisciplinary science, by uniting people with diverse expertise in immunology, biomedicine, bioengineering, systems and synthetic biology, computational biology, artificial intelligence and machine learning. As part of the mission of BIIE to make a lasting impact, it will dedicate significant efforts in training early-stage researchers in this unique multidisciplinary environment, thus enabling them to become future leaders in Immune Engineering.



The Botnar Institute of Immune Engineering is a newly founded non-profit research organization aiming to become a world leading research institute for the advanced study of immunological systems with a mission to develop translational solutions for the diagnosis, treatment and prevention of disease.

The scientific foundation of the BIIE is based on the intersection of three interdisciplinary subdomains: (i) systems immunology, (ii) synthetic immunology and (iii) computational immunology. The BIIE will serve as a hub for multidisciplinary science, by uniting people with diverse expertise in immunology, biomedicine, bioengineering, systems and synthetic biology, computational biology, artificial intelligence and machine learning. As part of the mission of BIIE to make a lasting impact, it will dedicate significant efforts in training early-stage researchers in this unique multidisciplinary environment, thus enabling them to become future leaders in Immune Engineering.



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