Lab Associate for Cellular Functional and Soluble Biomarkers

Vor 2 Tagen

Basel, Basel-Stadt, Schweiz Coopers Group AG Vollzeit
Lab Associate for Cellular Functional and Soluble Biomarkers (m/f/d)

Location: Basel

Contract duration: 1.5 years

Responsibilities:

  • As an Associate in Cellular and Functional Biomarkers, you will be an integral part of this mission — designing, developing, and transferring biomarker assays that support clinical trials. You will lead in-house assay development, support method transfers to external CRO partners, and ensure the generation of robust, high-quality biomarker data from method development through to clinical sample analysis.
  • Self-driven planning, development, troubleshooting and critical analysis of results of analytical methods for complex cellular, functional, and soluble protein biomarkers supporting preclinical and clinical drug development, in full compliance with regulatory and GxP requirements.
  • Design and execute experimental protocols, generate, analyze, troubleshoot, interpret data, and deliver high-quality reports aligned with project timelines.
  • Support method transfer and implementation with external partners, ensuring proper documentation and efficient troubleshooting.
  • Seek, evaluate and introduce novel technologies to enhance biomarker strategies and expand their application across therapeutic areas.
  • Collaborate with internal/external stakeholders to ensure data integrity, technical and scientific rigor, and timely resolution of technical challenges.
  • Presentations of activities and results on internal/external meetings.
  • Contribute to a culture of innovation, continuous improvement, and compliance with Safety, Security, Health, and Environmental (SHE) standards.

Requirements:

  • Bachelor's or Master's degree in a relevant scientific discipline, with proven industry or CRO experience.
  • Minimum of 2 years of experience in biomarker assay development within a regulated environment.
  • Proficiency across diverse biomarker assay technologies.
  • Cellular and functional assays: Flow cytometry, pFlow, ELISpot/FluoroSpot, HTRF.
  • Ligand-binding assays: ELISA, ELLA, Simoa, Elecsys, MSD.
  • Hands-on experience in technology implementation, optimization, and troubleshooting of bioanalytical/biomarker methods.
  • Strong understanding of GxP principles.
  • Experience supporting pharmacodynamic biomarker assay development for preclinical or clinical applications.
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