Scientist - Biology

Vor 4 Tagen

Basel, Basel-Stadt, Schweiz Novartis Vollzeit

Band

Level 3

Job Description Summary

Senior Scientist I, Oncology Translational Research

The Oncology Translational Research (OTR) Department at Novartis Biomedical Research is a global, laboratory-based research group, supporting the development of novel therapeutics in the Novartis Biomedical Research Oncology Disease Area.

Within OTR, the Oncology Pathology and Biomarkers (OPB) team leverages tissue-, cell-, and soluble protein–based assays to profile target epidemiology and biology, elucidate drug mechanisms of action, and define response/resistance biomarkers, from early target discovery through Phase 3 clinical development. OPB is seeking a motivated, inquisitive scientist to design and execute imaging-driven experiments that inform clinical biomarker strategies and accelerate Novartis Oncology drug candidates.


 

Job Description

The successful candidate will generate rigorous, high-quality data to propel translational research programs. By applying automated immunohistochemistry, immunofluorescence, and quantitative image analysis, they will help identify molecular predictors of response to cancer therapies, mechanisms of resistance or persistence under treatment, and opportunities for combination strategies.

Working closely with the lab head and team members, the candidate will flexibly contribute to both local and global projects and proactively share expertise across groups spanning the full Oncology portfolio, including radioligand therapeutics (RLT).

Key responsibilities:

  • Deliver high‐quality data to impact drug discovery and projects in clinical development

  • Design and conduct experiments and procedures requiring scientific and technical knowledge of immunohistochemistry and immunofluorescence

  • Devise new techniques around tissue-based biomarkers to advance drug development and early discovery programs

  • Supervise the development of multiplex IHC, FIHC and ISH assays

  • Conduct in-depth image analysis of whole slide images using established platforms

  • Consolidate, report data and present in context as needed

  • Efficiently manage and maintain a functional laboratory, technical equipment and reagents

  • Stay updated on the latest developments and trends in the field of Oncology and Radioligand Therapy

Role Requirements:

  • MSc or BSc or qualified Lab Technician in Biological Sciences or other relevant discipline with minimum 2 years of histology laboratory experience

  • Advanced/Fluent English oral and written

  • Must have experience developing singleplex and multiplex immunohistochemistry and immunofluorescence tissue-based assays

  • Proven experience with advanced image analysis using various software tools, including HALO

  • Experience working with cross-functional teams and demonstrated ability to independently drive projects in a matrixed environment

  • Knowledge of cancer signaling/biology is preferred, background in radioligand development and autoradiography is a plus

· Excellent organizational and communication skills

Languages :

  • English.

Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to and let us know the nature of your request and your contact information. Please include the job requisition number in your message


 

Skills Desired

Analytical Skill, Analytical Skill, Analytical Thinking, Chemical Biology, Chemistry, Clinical Research, Clinical Trials, Collaboration, Communication Skills, Curious Mindset, Data, Data Analysis, Design Of Experiments, Detail-Oriented, Diversity & Inclusion, Drug Discovery, Ethics, Gene Therapy, Immunology, Laboratory, Lifesciences, Machine Learning (ML), Mammalian Cell Culture, Medical Research, Molecular Biology {+ 11 more}

  • Scientist - Biology

    Vor 4 Tagen

    Basel, Basel-Stadt, Schweiz Novartis Vollzeit

    Job Description SummarySenior Scientist I, Oncology Translational ResearchThe Oncology Translational Research (OTR) Department at Novartis Biomedical Research is a global, laboratory-based research group, supporting the development of novel therapeutics in the Novartis Biomedical Research Oncology Disease Area.Within OTR, the Oncology Pathology and...

  • Scientist - Biology

    Vor 4 Tagen

    Basel, Basel-Stadt, Schweiz Novartis Vollzeit

    BandLevel 3Job Description SummarySenior Scientist I, Oncology Translational ResearchThe Oncology Translational Research (OTR) Department at Novartis Biomedical Research is a global, laboratory-based research group, supporting the development of novel therapeutics in the Novartis Biomedical Research Oncology Disease Area.Within OTR, the Oncology Pathology...

  • Scientist - Biology

    Vor 4 Tagen

    Basel, Basel-Stadt, Schweiz Novartis Vollzeit

    Job Description SummarySenior Scientist I, Oncology Translational ResearchThe Oncology Translational Research (OTR) Department at Novartis Biomedical Research is a global, laboratory-based research group, supporting the development of novel therapeutics in the Novartis Biomedical Research Oncology Disease Area.Within OTR, the Oncology Pathology and...

  • Computational Biology and Medicine- Ophthalmology

    vor 19 Stunden

    Basel, Basel-Stadt, Schweiz Roche Vollzeit

    Bei Roche kannst du ganz du selbst sein und wirst für deine einzigartigen Qualitäten geschätzt. Unsere Kultur fördert persönlichen Ausdruck, offenen Dialog und echte Verbindungen. Hier wirst du für das, was du bist, wertgeschätzt, akzeptiert und respektiert. Dies schafft ein Umfeld, in dem du sowohl persönlich als auch beruflich wachsen kannst....

  • Computational Biology and Medicine- Ophthalmology

    vor 1 Woche

    Basel, Basel-Stadt, Schweiz Roche Vollzeit

    At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure...

  • Computational Biology and Medicine- Ophthalmology

    vor 1 Woche

    Basel, Basel-Stadt, Schweiz Roche Vollzeit

    At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure...

  • PhD position in systems biology

    vor 19 Stunden

    Basel, Basel-Stadt, Schweiz Universität Basel Vollzeit

    The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need. With more than 70 research groups and 800 employees, the...

  • Post-Doc position in quantitative biology

    vor 20 Stunden

    Basel, Basel-Stadt, Schweiz Universität Basel Vollzeit

    The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need. With more than 70 research groups and 800 employees, the...

  • Applied/Senior Applied AI Scientist, Translational AI Lab

    vor 2 Wochen

    Basel, Basel-Stadt, Schweiz Roche Vollzeit $ 147'600 - $ 310'800

    A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.Advances in AI, data, and computational sciences are transforming drug discovery and...

  • Senior/Principal Applied AI Scientist, Translational AI Lab

    vor 1 Woche

    Basel, Basel-Stadt, Schweiz Roche Vollzeit $ 172'400 - $ 320'200

    A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.Advances in AI, data, and computational sciences are transforming drug discovery and...