Research Associate

NBE-Therapeutics is a subsidiary of the Boehringer Ingelheim group (BI): a perfect symbiosis between a rapidly growing biotechnology company and an already well-established big pharma. We are located in Basel, a Swiss city on the river Rhine, known for being an important center of chemical and pharmaceutical industries but also renowned for its versatile cultural aspects – a great place to live and work. Our research team is committed to the development of next generation antibody drug conjugates (ADCs) for cancer patients in need for new transformational treatments.

We look forward to receiving your application, including a motivation letter.

Please, send your documents to referring to job-opening: Ref251217

Job Description

You will support the discovery and development of novel cancer-targeting ADCs and in addition, help to address research questions associated with the respective ADC programs and the ADC technology using a wide variety of experimental approaches. We are looking for a motivated and independent team player who likes to work in a dynamic and friendly environment where everyone's performance has a direct impact on the success of the company.

Your Responsibilities

• Support defined ADC drug discovery and research projects independently and in collaboration with team members, supervisor and across teams
• Routinely culture and manipulate mammalian cell lines (e.g. genetic modification, flow cytometry and sorting, etc.)
• Conduct standard molecular biology experiments (Cloning, PCR etc.)
• Plan, execute and analyze cellular assays to screen and characterize ADC candidates (in vitro activity assays, internalization assays/IncuCyte, etc.)
• Perform analytical assays (Western blot, ELISA, FACS, etc.)
• Develop and optimize novel assays and technologies
• Carefully plan and execute experimental work, both independently and in collaboration with team members, supervisor and across teams
• Accurately and timely document experimental work in electronic lab book
• Prepare data summaries for meetings and reports
• Contribute to coordination of outsourced studies (CROs, external BI sites)
• Pro-actively contribute to lab organization to ensure optimal workflow

Your Profile

• MSc in Cell Biology, Molecular Biology, Biochemistry, Immunology or Biotechnology. The position is not suitable for candidates holding a PhD; thus their application cannot be considered.
• Work experience of 5 years or more.
• Curious and creative personality with persistence and a sincere aptitude for hands-on lab work and experimental design.
• Solid hands-on experience and knowledge in any of the areas of molecular biology, biochemistry, immunology or cell biology. Broad expertise in in vitro methods. Previous exposure to microscopy techniques, IHC assays or mass spectrometry-based analytics is an asset.
• Proactive, self-motivated person that is eager to learn, develop and implement new methodology and technology.
• Systematic, well-organized working style and extraordinary attention to detail throughout experimental and routine workflows.
• Team player with the ability to handle multiple work packages independently, in a dynamic work environment composed of international teams.
• Comfortable with preparing presentations to summarize and report own results.
• Diligent and respectful regarding general lab processes and organization.
• Solid knowledge of English (written and spoken) is a prerequisite; German is helpful but not essential.
• Residence in Basel or surrounding is key to flexibility and company success.

What we offer

• Exciting opportunities for development and professional growth within our dynamic organization
• An opportunity to make a difference on the way to safe people's life
• An innovative and open culture in a diverse and young environment

Who We Are and Our Culture

NBE-Therapeutics is an equal opportunity employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment, which benefits our employees, patients and communities.

In January 2021, NBE-Therapeutics joined as a subsidiary specialized in ADCs, the Boehringer Ingelheim group, which focuses on innovative medicines for people and animals since more than 140 years. Boehringer Ingelheim is one of the pharmaceutical industry's top 20 companies and to this day remains family owned. Day by day, more than 54'500 employees create value through innovation for the three business areas human pharmaceuticals, animal health and biopharmaceutical contract manufacturing. In 2024, Boehringer Ingelheim achieved a total revenue of 26.8 billion euros. The investments in R&D reached approximately 6.2 billion euros. This corresponds to 23.2% of consolidated net sales.

We look forward to receiving your application, including a motivation letter.

Please, send your documents to referring to job-opening: Ref251217