Executive Director, HEOR, Europe

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:
The Executive Director, HEOR Europe will lead the strategy, execution, and provide scientific leadership across health economics, outcomes research, and real-world evidence (RWE) to optimize the value demonstration of Revolution Medicines oncology portfolio across European markets. They will develop and lead a team of HEOR professionals across the EU and will work in concert with the Global HEOR and other regional teams to deliver an Integrated Evidence Plan for each asset and disease area. The role will align HEOR evidence generation with market access, pricing & reimbursement, patient access strategies, and cross-functional planning. The Executive Director, HEOR EU will report to the Global Head of HEOR, RWE and IEPs and will have dotted line reporting to the EU Head of Medical Affairs. They will sit on both the Global HEOR LT as well as the EU Medical LT. They will integrate across all the EU market leadership teams to ensure seamless communication and delivery

Key Responsibilities

• Strategic Leadership: Define and drive HEOR strategy across Europe in support of product lifecycle planning, value evidence generation, pricing/reimbursement, and access engagements. Lead or co-lead JCA preparation and dossier development as well as HTA engagement and preparation.
• Integrated Evidence Planning: Participate as the lead from EU within the Revolution Medicines IEP process and ensure the comprehensive plan achieves all needs for the EU markets.
• Evidence Generation & Analysis: Lead development of health economic models (cost-effectiveness, budget impact), real-world evidence, burden-of-disease assessments, and outcomes research programs that support regulatory filings, HTA submissions, and payer discussions.
• Cross-Functional Collaboration: Partner with Market Access, Medical Affairs, Commercial, Regulatory, and Clinical Development teams to ensure HEOR insights inform decision making across the product lifecycle.
• External Engagement: Represent Revolution Medicines in scientific, payer, and HTA forums; engage external stakeholders including key opinion leaders, academic collaborators, HTA bodies, and payers.
• Team & Vendor Leadership: Develop and lead an EU based HEOR team tasked with evidence generation across key markets; manage external collaborators (consultants, vendors) to support various HEOR projects within budget and timelines.
• Communication: Communicate HEOR strategy, research outcomes, and value propositions to internal leadership (including European and global functions) and external audiences.

Required Skills, Experience and Education:

• Advanced degree (PhD, MSc, MPH, or equivalent) in Health Economics, Epidemiology, Pharmacoeconomics, Biostatistics, Public Health, or related discipline.
• Extensive HEOR experience (15+ years) in pharmaceutical/biotech/consulting settings with significant leadership exposure.
• Demonstrated expertise in health economic modeling, RWE study design, outcomes research methodologies, and HTA submission experience.
• Strong scientific credibility, strategic vision, and ability to influence cross-functional and external stakeholders
• Excellent communication and leadership skills with experience presenting at scientific and payer forums.

Preferred Skills:

• Demonstrated ability to drive success through cross-functional team leadership and team motivation.

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