Internship - Downstream process development for oligonucleotides (12 Monate)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

At Roche, we are committed to delivering medical solutions today while innovating for the future. We are passionate about transforming patients' lives and act with courage and purpose.

Pharma Global Technical Operations (PT) supports every product from Phase I to maturity, with over 10,000 employees worldwide. In Global Technical Development (PTD), we develop creative technical solutions to efficiently transform scientific ideas into products, ensuring reliable delivery of quality medicines.

Synthetic Molecules Technical Development (PTDC) focuses on the technical development of synthetic pipeline molecules and the manufacture of Drug Substance and Drug Product for clinical studies. PTDC combines expertise across development and analytical sciences and collaborates closely with Research & Early Development (pRED/gRED) and the synthetic molecules commercial manufacturing network.

The opportunity

• Supporting process development of oligonucleotide manufacturing, focusing on downstream processes
• Developing preparative chromatographic purification processes, including screening conditions and performing purifications
• Conducting analytical tests to evaluate purity and quality of products
• Analyzing and interpret experimental data to optimize processes
• Collaborating with cross-functional teams for successful process implementation
• Participating in team meetings, problem-solving discussions, and present results
• Documenting experimental procedures, results, and observations clearly and accurately
• Gaining hands-on experience through a 12-month internship in the biopharmaceutical industry
• Receiving mentorship, training, and exposure to cutting-edge technologies in a collaborative environment

Who you are

• Enrolled as a Master's student or completed Master's studies within the last year in Chemistry, Biochemistry, Chemical Engineering, or a related field
• Strong understanding of organic chemistry, chromatography, and process chemistry
• Hands-on laboratory experience
• Initiative-driven, responsible, flexible, and team-oriented working style
• Ideally, experience with oligonucleotide chemistry, chromatography, or ultrafiltration

• Fluent in English or German

• Start date: February or March 2026

• Workload: 100%
• Duration: 12 months
• Location: Basel

We kindly ask you to provide a motivation letter, a current CV, and your enrollment certificate/proof of qualifications.

Due to regulations non-EU/EFTA citizens must provide a certificate from the university stating that an internship is mandatory as part of the application.

Apply now - we look forward to hearing from you

Who we are

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let's build a healthier future, together.

Roche is an Equal Opportunity Employer.