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Laboratory Technician, in Vivo
vor 2 Wochen
NBE Therapeutics is a subsidiary of the Boehringer Ingelheim group: a perfect symbiosis between a rapidly growing biotechnology company and an already well established big pharma. We are located in Basel, a Swiss city on the river Rhine, known for being an important center of chemical and pharmaceutical industries but also renowned for its versatile cultural aspects - a great place to live and work. Our Research Team is committed to the development of next generation antibody drug conjugates for the treatment of cancer. We are looking for a highly motivated:
**Laboratory Technician, **_in vivo_**
**Your tasks**
- Perform _in vivo_ experimental models of cancer in mice, including:
- Delivery of drug compounds and cells using various routes of administration (IV, PO, SC, IV, IP)
- Assessment of animal health throughout the study (health checks, clinical observations)
- Periodic measurements of bodyweights and tumors
- Harvest and preparation of tumor samples
- _Ex vivo _processing of_ in vivo _material (e.g. with gentleMACS dissociator)
- Development and validation of new animal models, and _ex-vivo_ and _in-vitro_ assays according to the need of the department
- Skilled in basic _in vitro_ techniques such as FACS, ELISA, Western-Blot, cell culture assays
- Independent planning, execution documentation of experiments and interpretation of results
- Review relevant literature to optimize experimental methods, stimulate new ideas and develop new assays for experimental studies
- Presentation of results within a multidisciplinary team environment
- Contribute to the general lab infrastructure, including ordering of consumables, and coordinating with colleagues the workflow, organization, maintenance, and function of lab resource
**Your Profile**
- Laboratory Technician or Bachelor in Biology with certified training in animal work
- 1-3 years work experience and knowledge of preclinical _in vivo_ models
- Officially recognized as animal experimenter (LTK1 or equivalent) by the Federal Veterinary Office
- Practical background in different _in vitro_ techniques (FACS, ELISA, primary cell culture handling, SDS-PAGE, Western blot)
- Flexible person and keen to learn new skills and techniques
- Ability to work independently, flexibility with regard to working-hours and ability to accommodate changing priorities, timelines or tasks
- Good oral and written communication skills in English; additional knowledge of German preferred
- Well trained in computer programs: Excel, Power Point, Word, GraphPad Prism, FlowJo
**What we offer**
- Exciting opportunities for development and professional growth within our dynamic organization
- An opportunity to make a difference on the way to safe peoples life
- An innovative and open culture in a diverse and young environment
