Intern - Virus Quantification for Dsp Optimization

vor 2 Wochen


CorsiersurVevey, Schweiz Merck KGaA Darmstadt Germany Vollzeit

Work Your Magic with us

Ready to explore, break barriers, and discover more? We know you've got big plans - so do we Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

**Your role**:
As part of the Global Drug Substance Development department, you will join a team of motivated scientists dedicated to create and implement innovative solutions to support the development and manufacturing of new biological therapeutics. Viral validation is a key part of the process development and validation activities to ensure patient safety. Viral clearance needs to be evaluated for two main objectives:

- To support investigational studies evaluating the effect of new resins or non-platform conditions on viral clearance during process development activities

Viral clearance studies are conducted at a separate laboratory which is equipped to carry out virological activities and separated from the production site to avoid contamination of CHO cells culture used for production by the viruses used in the viral clearance studies. For these reasons, viral clearance studies are tedious and extremely costly. Your mission will focus on the evaluation of an innovative immuno-qPCR kit using non-infectious viral-like particles to evaluate the viral clearance capacity of a DSP purification step, to support in-house investigational viral clearance studies. You will design and execute laboratory experiments in collaboration with development, innovation and analytical teams. You will be trained to be autonomous and will have the opportunity to present your work during various meetings.

**Your profile**:

- Master/engineer student in Biotechnology or related fields
- Highly motivated and autonomous
- Ability to conceptualize, solve complex challenges and to communicate about your project
- Great team spirit
- Previous experience in DSP is a plus
- Good written and oral knowledge in English, French is a plus

**What we offer**:We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress



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