Postdoctoral Researcher in Biomedical Research

**Institute of Anatomy**
**Postdoctoral Researcher in Biomedical Research 100 %**: Start of employment by arrangement, ideally before August 1st 2025.

The institute of Anatomy combines modern biomedical research with training the next generation of medical professionals. As a postdoctoral researcher, you will join a team focused on using amphibian models (Xenopus tropicalis and laevis) to explore the molecular mechanisms of inherited diseases, a dynamic field, where your contribution can make a real difference.

We recently pioneered new tools for targeted genomic integration to generate custom transgenic lines and endogenously tag proteins of interest (Naert, et al., BioRxiv, 2024). We will employ these tools in combination with advanced imaging techniques and analysis tools (Naert, et al., Development, 2021) to explore the in vivo functions of proteins related to congenital diseases, including genetic kidney diseases and ciliopathies.

**Your responsibilities**:

- Your main objective will be to conduct innovative research into the molecular mechanisms of genetic diseases employing novel models and genome engineering in Xenopus. You will use key technologies, such as light-sheet imaging, live imaging, automated image analysis, CRISPR knockout or integration in Xenopus embryos. You are welcome to contribute your own ideas and actively shape the project.

**Your profile**:
What we offer:
Our collaborative, well-funded research team values communication, and an inspiring work environment. We offer an exciting research project in a clinically relevant field funded by the SNSF. We have a track record of uncovering pathomechanisms of genetic disease (Hoff et al., Nat. Genetics, 2013; Getwan, et al., PNAS, 2021) and technological advancements (Voigt et al., Nat. Biotech, 2024; Vladimirov, et al., Nat. Comm, 2024).
Our group is well integrated in the local research environment, member of the Zurich Kidney Center, and well connected to the international Kidney and Xenopus communities, with access to outstanding scientific infrastructure and core facilities at both the University of Zurich and the ETH Zurich.
We offer excellent opportunities to pursue a career in or outside of academia.

**What we offer**:
**Work-Life Balance**
- Flexible working models (such as part-time positions, mobile working, job-sharing)
- Childcare at the kihz foundation of UZH and ETH

**Learning and Development**
- Wide range of continuing education courses of UZH and the Canton of Zurich
- Language Center run jointly with ETH Zurich

**Food**
- Food and drinks at reduced prices in the UZH cafeterias
- Lunch-Check-card with UZH contribution

**Healthcare**
- Special conditions on the Academic Sports Association ASVZ
- Free seasonal flu vaccinations
- Rest and relaxation at the quiet room in the university tower

**Discounts**
- Private traffic: Carsharing, rent a vehicle, parking space
- Digitalization: Hardware, software, mobile phone subscriptions
- Special conditions on hotel reservations

**Conditions of Employment**
- Policies of the UZH
- Most UZH staff are employed according to public law

**International Services**
- Support for people from outside Switzerland

**Campuses**
- Campuses Zurich City, Zurich Irchel, Oerlikon and Schlieren
- Sites Zurich West, Old Botanical Garden, Botanical Garden and Lengg

**Location**:
**Institute of Anatomy***:Winterthurerstrasse 190, 8057 Zürich, Switzerland

**Further information**:
**Questions about the job**:
**Prof. Dr. Soeren Lienkamp**
- Head of research group Renal Development and Reprogramming

**Working at UZH**: