PhD position in Molecular Biology

vor 1 Woche


Zürich, Schweiz Institute of Molecular Biology & Biophysics, ETH Zurich Vollzeit

Job description We are looking for an enthusiastic and highly-motivated candidate to investigate how the microtubule cytoskeleton is regulated by protein complexes such as the gamma-TuRC. Potential projects goals will include, but are not limited to, using structural biology methods such as cryo-electron microscopy and X-ray crystallography, as well as single molecule light microscopy such as Total Internal Reflection Fluorescence (TIRF), to visualize components of the gamma-TuRC as the complex nucleates microtubules. The group has access to state-of-the-art light and electron microscopy instrumentation, including a Nikon N-STORM equipped for TIRF microscopy and multiple Titan Krios EM scopes, all hosted and maintained at ETH Zurich’s imaging facility, ScopeM. This is a fully funded position for 4 years with an anticipated start date of September 1st, (negotiable). Further project details will be discussed further in the interview. Profile Research interest in cell biology, structural biology, biochemistry and/or biophysics Curiosity about the inner workings of the cell and a passion for basic science are a plus Experience with basic molecular biology, cell culturing, and/or protein purification methods are a plus Experience with cryo-EM sample preparation and structure determination using various modern software tools (e.g. cryoSPARC and RELION) are a plus An MSc degree in biochemistry, cell biology, structural biology, biophysics, or disciplines related to the PhD position The writing of scientific papers and active participation in internal meetings and in international conferences will require a good knowledge of English Workplace Workplace We offer



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