Senior Pharmacometrician

Debiopharm, a privately-owned Swiss biopharmaceutical company, is seeking a highly skilled Senior Pharmacometrician to join its Clinical Pharmacology and Pharmacometrics Unit. As a key member of our team, you will contribute to the development of innovative medicines for patients suffering from cancer and infectious diseases.

About the Role

• Conduct pharmacometric analyses of nonclinical and clinical data using innovative quantitative methods to support model-informed drug development in early to late clinical phases of oncology and antibiotics projects.
• Develop and execute PK/PD modeling and simulation strategies to facilitate quantitative decision-making in support of projects.
• Manage pharmacometrics activities of assigned projects, directly or in collaboration with external vendors, in compliance with regulatory guidelines.
• Collaborate with Clinical Pharmacology and relevant functions within Translational Medicine and Research & Development to support study design, dose selection, and optimization for small and large molecules under development.
• Prepare pharmacometrics documentation to support regulatory or other cross-functional activities.

Requirements

• PhD or equivalent degree in pharmaceutical sciences, mathematics, statistics, engineering, or similar disciplines with demonstrated expertise in pharmacometrics.
• Excellent programming skills (R, Python,...) and solid hands-on experience in Population PK/PD modeling softwares (Monolix, NONMEM).
• In-depth understanding of pharmacology and pharmacokinetic concepts, as well as knowledge of preclinical and clinical development.
• At least 3-5 years relevant experience within industry or academia; experience in oncology and/or antibiotics is an asset.
• Knowledge of GCP, GCLP, and relevant regulatory guidelines.

What We Offer

• International, highly dynamic environment with a long-term vision.
• Cross-functional collaboration at the forefront of the most advanced scientific developments in oncology and anti-bacterial industry.
• Exposure to a wide variety of areas and functions within clinical development and the pharmaceutical industry.
• Opportunity of personal development through specific trainings and attendance to scientific conferences.

How to Apply

Please submit your application through our website. We thank all applicants for their interest; however, only those selected for an interview will be contacted.