Brain Delivery Specialist

vor 2 Wochen


Basel, Basel-Stadt, Schweiz Roche Vollzeit

Company Overview

At Roche Pharmaceutical Research and Early Development Organization, we are driven by a passion to address some of the world's most pressing health challenges. Our teams collaborate across departments and locations to advance cutting-edge technologies and develop innovative therapies.

Job Description

We are seeking an experienced Brain Delivery Specialist to join our team at the Roche Innovation Center Basel. As a key member of our Neuroscience department, you will contribute to advancing exploratory and preclinical projects focused on improving antibody delivery to the brain.

Responsibilities:

  • Maintain human iPSC-derived cell types of the neurovascular unit, including generation and characterization of CRISPR gene-edited lines.
  • Develop and execute experiments independently and in collaboration with other groups to advance our understanding of novel therapies for neurodegenerative disorders.
  • Analyze, interpret, and document data, communicating results in team and departmental meetings.
  • Contribute to lab management and organization, ensuring efficient workflows and effective teamwork.

Qualifications:

  • Bachelor's or Master's degree in Life Sciences (Biology, Biotechnology) or relevant area with at least 2 years of wet lab experience.
  • Strong background in human cell culture, preferably using stem cells.
  • Expertise in molecular cell biology methods, including Western Blot, ELISA, confocal microscopy, cloning, and transfections.
  • Hands-on experience with fluorescent or luminescent reporters and/or sensors is beneficial.
  • Basic knowledge of image analysis software (Fiji) and data analysis tools (Prism).
  • Able to design, execute, and analyze experiments independently.
  • Strong critical thinking, communication, organization, and presentation skills.

General Qualifications:

  • Excellent computer-based data management and record-keeping skills; basic biostatistical data analysis is a plus.
  • Excellent communication skills to report results to the team; good command of English language (speaking and writing) is required.
  • Ability to work independently and troubleshoot in a multi-departmental and international pharma research environment.
  • Motivation to build Matrix-leadership skills and adapt to changing priorities.

Compensation:

The estimated annual salary for this position is between $85,000 and $110,000, depending on qualifications and experience.



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