Brain Delivery Specialist
vor 2 Wochen
Company Overview
At Roche Pharmaceutical Research and Early Development Organization, we are driven by a passion to address some of the world's most pressing health challenges. Our teams collaborate across departments and locations to advance cutting-edge technologies and develop innovative therapies.
Job Description
We are seeking an experienced Brain Delivery Specialist to join our team at the Roche Innovation Center Basel. As a key member of our Neuroscience department, you will contribute to advancing exploratory and preclinical projects focused on improving antibody delivery to the brain.
Responsibilities:
- Maintain human iPSC-derived cell types of the neurovascular unit, including generation and characterization of CRISPR gene-edited lines.
- Develop and execute experiments independently and in collaboration with other groups to advance our understanding of novel therapies for neurodegenerative disorders.
- Analyze, interpret, and document data, communicating results in team and departmental meetings.
- Contribute to lab management and organization, ensuring efficient workflows and effective teamwork.
Qualifications:
- Bachelor's or Master's degree in Life Sciences (Biology, Biotechnology) or relevant area with at least 2 years of wet lab experience.
- Strong background in human cell culture, preferably using stem cells.
- Expertise in molecular cell biology methods, including Western Blot, ELISA, confocal microscopy, cloning, and transfections.
- Hands-on experience with fluorescent or luminescent reporters and/or sensors is beneficial.
- Basic knowledge of image analysis software (Fiji) and data analysis tools (Prism).
- Able to design, execute, and analyze experiments independently.
- Strong critical thinking, communication, organization, and presentation skills.
General Qualifications:
- Excellent computer-based data management and record-keeping skills; basic biostatistical data analysis is a plus.
- Excellent communication skills to report results to the team; good command of English language (speaking and writing) is required.
- Ability to work independently and troubleshoot in a multi-departmental and international pharma research environment.
- Motivation to build Matrix-leadership skills and adapt to changing priorities.
Compensation:
The estimated annual salary for this position is between $85,000 and $110,000, depending on qualifications and experience.
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