PhD Student in Ophthalmology Research
Vor 5 Tagen
The Department of Ophthalmology at the Universität Bern is a leading center for state-of-the-art diagnostics, therapy, and microsurgery of eye diseases and ophthalmologic emergencies. Our research group focuses on the employment of Müller cells as potential candidates for replacing degenerated photoreceptors.
We are investigating the active modulation of Müller cell transition as a pivotal process during degeneration/regeneration and the treatment of chronic gliosis in mice. Our findings show similarities to wound healing (fibrosis). Additionally, we have established a human retinal organoid degeneration model to study the role of Müller cell response.
The PhD project aims at pathway analysis in animal models with retinal degeneration, investigating cell type-associated differential gene expression, and pharmacological treatment and/or gene editing in regard to the identified pathways.
The experimental spectrum of the PhD project will include classic methods in molecular and cell biology as well as in vivo experiments including mice and zebrafish and iPSC-derived or other cell-based systems. Bioinformatic evaluation of the data in collaboration with computer scientists will occur.
We are looking for highly motivated, interactive, and team-oriented candidates with a high degree of self-initiative and inventiveness. Applicants should hold a master's degree in biology, biomedical sciences, or related fields, preferably with background knowledge in neurobiology and/or cell biology.
The interesting and challenging project will be performed in a dynamic team and a creative research environment with a broad spectrum of methodology and further advanced training opportunities. The applicant will join the Graduate School for Cellular and Biomedical Sciences to complement her/his training.
For subject-specific questions and information about the position, please contact Prof. Dr. Volker Enzmann. Please send your application with the usual documents electronically to the following e-mail address.
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