Senior Pharmacometrician

Debiopharm is a Swiss biopharmaceutical company dedicated to research in oncology and infectious diseases to improve patient outcomes and quality of life. Our unique "development only" business model enables us to act as a bridge between innovative discovery products and patient access in international markets.

We are seeking a Senior Pharmacometrician to join our Clinical Pharmacology & Pharmacometrics Unit organization based at our Headquarters in Lausanne. As a key member of our team, you will be at the forefront of the fight against cancer and infectious diseases, working on innovative medicines for patients.

Your responsibilities will include:

• Conducting pharmacometric analyses of nonclinical and clinical data using innovative quantitative methods, modeling pharmacokinetics, pharmacodynamics, biomarkers, and clinical outcomes data.
• Contributing to the elaboration and execution of PK/PD modeling and simulation strategies to support model-informed drug development in early to late clinical phases of oncology and antibiotics projects.
• Managing pharmacometrics activities of assigned projects, directly or in collaboration with external vendors, in compliance with regulatory guidelines.
• Collaborating with Clinical Pharmacology and relevant functions within Translational Medicine and Research & Development to support study design, dose selection, and optimization for small and large molecules under development.
• Preparing pharmacometrics documentation to support regulatory or other cross-functional activities, and participating in interactions with Health Authorities.
• Contributing to scientific communications and events.

Requirements

• PhD or equivalent degree in pharmaceutical sciences, mathematics, statistics, engineering, or similar disciplines with demonstrated expertise in pharmacometrics.
• Excellent programming skills and solid hands-on experience in Population PK/PD modeling software.
• In-depth understanding of pharmacology and pharmacokinetic concepts, as well as knowledge of preclinical and clinical development.
• At least 3-5 years of relevant experience within industry or academia, with experience in oncology and/or antibiotics being an asset.
• Knowledge of GCP, GCLP, and relevant regulatory guidelines.
• Ability to work independently while maintaining strong collaborations within cross-functional teams.
• Strong organizational skills and ability to handle multiple tasks simultaneously.
• Excellent presentation capabilities and communication skills in English, with French being an asset.

Benefits

• International, highly dynamic environment with a long-term vision.
• Cross-functional collaboration at the forefront of the most advanced scientific developments in oncology and anti-bacterial industry.
• Exposure to a wide variety of areas and functions within clinical development and the pharmaceutical industry.
• Opportunity for personal development through specific trainings and attendance to scientific conferences.
• Participation in a company where innovation, people, and entrepreneurship are the fundamental keys to success.
• Proud to be an Equal-Pay certified company, ensuring equal opportunities for all employees.