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Chemical Biology Expert Wanted

vor 2 Wochen


Stäfa, Zürich, Schweiz Eidgenössische Technische Hochschule Zürich Vollzeit

We are looking for a talented scientist to investigate the dissection of the mode of action of bioactive compounds. As a member of our team, you will be part of a dynamic and international working atmosphere with excellent research infrastructure.

About the Project

Omphalotin A, a ribosomally synthesized dodecapeptide macrocycle, displays toxicity towards the root-knot nematode Meloidogyne incognita. Additionally, it shows immunomodulatory activity similar to cyclosporin A. Our hypothesis is that omphalotin A targets a different intracellular protein of immune cells to exert its function.

To address this question, we plan to use two different proteomics approaches to identify the target protein of omphalotin A in immune cells.