Encoded Peptide Screening Specialist

Vor 7 Tagen


Basel, Basel-Stadt, Schweiz C028 (FCRS = CH028) Novartis Pharma AG Vollzeit

Become a Part of Our Innovative Team

We are a highly collaborative, global group of researchers exploring the interface of chemistry and biology for projects in early drug discovery. The Chemical Genetics group in DSc, Basel/Switzerland, is seeking a highly motivated, curious, and innovative research scientist.

About the Position:

Our team applies and develops encoded library technologies for the discovery of low molecular weight and peptide binders to disease-relevant targets and explores emerging drug modalities as novel innovative paths to therapeutics.

Your Key Responsibilities:

  • Conducting all experimental aspects of peptide mRNA-display for drug discovery projects with an emphasis on Radioligand therapy and siRNA projects: preparing and analyzing reagents for platform execution, executing encoded peptide library screening campaigns manually and using lab automation, interpreting results, recognizing when procedures are not working and providing explanations and/or solutions.
  • Innovating and further developing existing encoded library technologies, proposing and exploring novel experimental alternatives.
  • Analyzing experimental data and communicating results at internal meetings.
  • Working closely within multidisciplinary, collaborative project teams and contributing to a constructive team environment.
  • Contributing efficiently to the maintenance of a functional laboratory and technical equipment.

Requirements:

  • A Master's equivalent (e.g., university degree, etc.) in a scientific discipline such as biology, chemistry, or pharmacology; or a Bachelor's degree/apprenticeship (or equivalent) with appropriate and relevant experience in drug discovery.
  • Strong wet-lab experience in molecular biology, biochemistry, and biophysics, particularly in manipulating and analyzing oligonucleotides and proteins.
  • An interest in working with medium throughput lab automation.
  • The ability to adapt to scientific challenges and generate innovative solutions.
  • An affinity towards exploring novel technologies and therapeutic approaches for drug discovery.


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