Junior PAT Expert

Vor 3 Tagen

Basel, Schweiz Roche Vollzeit

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

202412-131091 Junior PAT Expert (Process Analytical Technology) – 3 year temporary position

We advance science so that we all have more time with the people we love.

Within “Synthetic Molecules Technical Development” our Process Analytical Technology (PAT) group is responsible for the implementation of PAT tools to support a fast and effective drug substance and drug product process development of our pipeline projects. We are also developing and validating PAT procedures for Real Time Release Testing (RTRT) and support novel technology platforms (e.g. continuous manufacturing) with dedicated PAT solutions.

We are looking for an inquisitive candidate who easily connects with people and is keen to make a difference. In order to successfully support our PAT team in the dynamic development environment here at Roche in Basel, you will bring passion and commitment, openness for working in teams, a “can do” attitude, and a mindset of helping others.

The Opportunity

As Junior PAT Expert, you will support the development, validation and implementation of PAT in R&D, clinical and commercial manufacturing. You will report to the Head of Process Analytical Technology.

Main responsibilities are (with support from Senior PAT experts):

- Development of qualitative and quantitative chemometric models

- Hands-on setup of PAT tools in laboratory and production

- Running experiments in the team or independently

- Validation of PAT methods & GMP compliance

- Authoring of development & validation reports, SOPs and regulatory documents

Who you are

As the ideal candidate, you will either hold a PhD in Natural Sciences or Engineering. Alternatively you own a MSc degree in Natural Sciences or Engineering in combination with 1-3 years professional experience. You are expected to bring the following skillset:

- Expertise in spectroscopy (e.g. NIR, IR, Raman) and analytical techniques for on-line process monitoring (e.g. NMR, online LC)

- Hands-on laboratory experience, specifically in performing PAT measurements (at-line, on-line, in-line)

- Data & modeling skills (e.g. chemometric modeling, multivariate data analysis)

- Matlab/Python/R/C++ programming skills & high affinity to digital tools

- Excellent communication skills in English and /or German (ideally both)

- High level of motivation and ability to implement pragmatic solutions

Additional skills or experience in the following areas are a plus:

- Data science, data engineering

- Process automation

- Continuous manufacturing

- Small molecule, peptide or oligonucleotide process knowledge

- Knowledge/expertise in GMP and regulatory guidelines

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.

Roche is an Equal Opportunity Employer.

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