Phd Student Position in Topic Molecular

vor 3 Wochen


Bern, Schweiz Universität Bern Universität Bern Vollzeit

**PhD student position in topic molecular endocrinology**:
**AdmiR3 - Solving the mystery of adrenarche in human sexual development**
**PhD student position: Find possible mechanisms and new markers of adrenarche, a prepubertal event of human sexual development**

**100%, starting date 01.01.2023 or later**:
The aim of the SNF-funded project “AdmiR3” is to understand fundamental mechanisms regulating human adrenarche, a critical prepubertal event in human sexual development. With multi-omics approaches we will investigate human biomaterials and perform cellbased studies in order to understand underlying mechanisms of regulation of this event in health and disease.

Tasks
- Generation and analysis of transcriptome profiles to investigate the impact of small and messenger RNAs in human

adrenarche
- Use of multiple animal models to interrogate the conservation of hypothesisdriven mechanisms of adrenarche

across species
- Chemical and genetic manipulation in human cell models of androgen biosynthesis, including reprogrammed

iPSCs, for investigating the fine molecular mechanisms of adrenarche
- Support and preparation of scientific reports and journal articles

**Requirements**:

- Master's degree in (Bio)Physics, (Bio)engineering, Biological Sciences,
- Microbiology, Biochemistry, Systems Biology, Molecular Biology, Bioinformatics/Computational Biology, or related

fields
- Experience with basic wet laboratory techniques
- Hands-on experience with key biochemical and molecular biological methods
- Motivation to work in an international research environment
- Strong motivation to learn and commitment to science
- Good communication skills

We offer
- You will follow a highly recognized PhD training program at the GCB of the University of Bern
- You will have access to state-of-the-art research equipment in metabolomics, cell biology and bioinformatics
- You will work in a dynamic and interdisciplinary team
- You will be involved in cross-disciplinary collaborations and have training opportunities to further develop and grow

your scientific interests
- Opportunity to work in close contact with other basic
- and clinical-researchers within the Flück/Pandey groups at

the Department of Biomedicine Research and the Department of Pediatrics
- Support from experienced team members

A) a cover/motivation letter
B) a complete curriculum vitae



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