Organoid Automation Scientist

**Beschreibung**:
For our international partner, Roche Diagnostics International Ltd. based in Rotkreuz, we are looking for a qualified and motivated **Organoid Automation Scientist** for 2 years with option for extension.

In Roche Pharmaceutical Research and Early Development Organization (pRED) we believe the rapid advances in science, technology, digital and big data are our greatest opportunity to rethink how we tackle some of the world’s toughest unmet health care needs and to have an even more profound impact on patients and society.

At pRED we are united by our mission to transform science into medicines. Together we create a culture defined by curiosity, responsibility and humility where our amazing people are empowered and inspired to bring forward amazing innovation at speed.

The Automation Scientist for the Roche Institute for Translational Bioengineering (ITB) will support the establishment of a newly formed initiative in pRED whose goal is to disrupt the traditional drug discovery process through innovation/big and bold ideas focused on advancing our ability to use more predictive human model systems. The automation scientist will contribute to the prototyping of human in-vitro cultures on a robotic platform. As a member of multidisciplinary team, she/he will design, evaluate and deploy state-of-the-art in-vitro culture protocols in a lab framework. The Automation Scientist will work in close collaboration with other researchers to develop standard operating procedures (SOP) for the culturing of in-vitro models. This is a rare opportunity to be involved in supporting the creation and growth of a new and exciting institute that brings together scientists and engineers from around the world.

**Tasks**:

- Survey scientific literature for state-of-the-art organoid culture protocols
- Implement, adapt and improve existing organoid culture protocols on the robotic platform
- Develop SOPs to be implemented in an organoid manufacturing facility
- Contribute to the improvement of existing automation procedures
- Assist other research groups in the development and implementation of new procedures and in the evaluation of new products and equipment
- Assume responsibility for the accuracy, quality and timeliness of organoid farming and phenotyping activities
- Participate in the planning and organization of experiments in collaboration with the team
- Assist in the preparation of experimental protocols, investigations and reports as appropriate
- Train, mentor, or supervise junior scientists within the work team

**Must Haves**:

- MSc or PhD in biology, biochemistry or biomedical engineering and experience in automation
- Minimum 3 years of experience in automation, preferable using liquid handlers or bioreactor systems
- Experience with liquid handlers (hamilton devices preferred) and with integration systems
- Good programming skills (Python, C++, Liquid handler workflows, etc ).
- You have good English communication skills and love to work collaboratively in an international team

**Nice to Haves**:

- Experience with organoids or in-vitro biological systems
- Experience with bioreactors
- Experience with scheduling software
- Experience with image analysis and machine learning algorithms
- Experience with high content imaging microscopes