Scientific Expert in Polymorphism and Particle

vor 2 Wochen


Basel, Schweiz Novartis Vollzeit

105,000 The number of unique individuals who work at Novartis, all with different needs and aspirations, aligned to a single inspirational purpose: to Reimagine Medicine for millions of patients around the world

You will play a key role in strengthening scientific excellence at the interface between drug substance and drug product development. You will bring with you an understanding of requirements for the salt and polymorphism selection, particle and powder properties to support project teams operating in both early and late phase development.
In addition, you will collaborate alongside experts for the preparation of drug substances and drug products to develop, assess and optimize the physical properties of a drug substance for subsequent use in drug product development.
Your key responsibilities will include:

- Ensure the appropriate selection, development, and characterization of solid forms of an API during early and late phase product development
- Develop crystallization manufacturing processes to deliver drug substances in line with drug product needs.
- Drive cross-team and cross-functional knowledge exchange in the areas of API form selection, particle design and characterization (e.g. salt and polymorph selection, crystallization development, powder properties) through coaching to expand the skill base relating to Materials Science.
- Be an advocate for strengthening the interface between drug substance and drug product development within the Materials Science unit, project teams and across functions.

**Commitment to Diversity & Inclusion**:

- We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._

**Minimum requirements**
- PhD in relevant scientific field (e.g. crystallography, materials science, physical chemistry)
- Broad scientific and technical knowledge in appropriate analytical technologies used for API and powder characterization (e.g. x-ray powder diffraction, thermal analysis, laser light diffraction, dynamic vapor sorption, dynamic light scattering, microcalorimetry).
- Good knowledge of appropriate modelling tools.
- Experience in the stage appropriate requirements in drug substance and drug product technical development from early to late stage development.
- Strong communication, negotiation, presentation, technical writing, coaching skills. Desire to help associates grow in new and existing roles.
- Interdisciplinary thinking and strength in cross-functional collaboration.
- Experience in working and managing complex stakeholder environments across line functions.
- Excellent planning and work prioritization skills.
- Familiarity with GMP requirements would be advantageous.
- English (fluent) required. German desirable.

Why Novartis?

769 million lives were touched by Novartis medicines in 2020, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying

Imagine what you could do here at Novartis

**Division**

Global Drug Development

**Business Unit**

TECHNICAL R & D GDD

**Country**

Switzerland

**Work Location**

Basel

**Company/Legal Entity**

Novartis Pharma AG

**Functional Area**

Research & Development

**Job Type**

Full Time

**Employment Type**

Regular

**Shift Work**

No

**Early Talent**

No


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