Postdoc in Molecular/chemical Biology Ft

vor 2 Wochen


Zurich, Schweiz University of Zurich, Department of Chemistry Vollzeit

**The project and you**

The Photochemistry Group at the Department of Chemistry, University of Zurich is looking for a postdoctoral researcher to join our team. Our interdisciplinary research combines organic chemistry, photochemistry and biology, and strives to expand the boundaries of applied photochemistry. We re-engineer existing organic dyes into photocages that release and activate organic molecules when triggered with tissue-penetrating NIR light, and transform them into precision-guided nanotherapeutic systems. Our ultimate goal is to push the frontiers of medicine and enable next-generation, personalized therapy by unlocking novel therapeutic avenues, or by enhancing those that already exist. The position is funded by Swiss Cancer League.

In this project, **you will investigate light-controlled nanotherapeutics that carry FDA-approved drugs as a warhead **in human cancer cell lines and models. You will study and evaluate their performance, selectivity, pharmacokinetic properties, and compare them to the existing drugs/prodrugs.

**Who you are**

A highly motivated, creative, responsible and ambitious individual with critical thinking and attention to a detail. A friendly team player capable of scoring in the overtime when the team needs you the most. You have:

- First class PhD degree in molecular/chemical biology or biochemistry, awarded prior to the start of the contract.
- Excellent background in biology and biochemistry, including working with human (cancer) cell lines.
- Extensive experience with cell viability studies, cellular uptake/efflux studies, western blot, gene knockout, transfection/transduction techniques, flow cytometry and 3D tumor models is essential for the project. Experience with bioimaging is an advantage.
- Experience with grant and publication writing.
- Academic awards at university or national level.
- Excellent written and oral English skills, German language is an advantage.

**What we offer**
- A crazy voyage into the realm of photochemistry in the near-infrared territory and drug delivery as a part of a tightly-knit, motivated and friendly team.
- Academic salary corresponding to the UZH regulations.
- State-of-the-art research infrastructure.
- International collaborations, conferences, training and mentoring.
- Options to develop skills in other areas - computer graphics and 3D modelling in science, 3D-printing.
- Place of work: Irchel Campus, Winterthurerstrasse190, CH-8057, Zurich.

**Application**

**Job Types**: 80-100%, Fixed term
Contract length: 12 months

**Salary**: CHF70,000.00 - CHF80,000.00 per year

Schedule:

- Day shift
- Monday to Friday

Ability to commute/relocate:

- 8057 Zürich, ZH: Reliably commute or planning to relocate before starting work (required)

**Education**:

- Doctorate (required)

**Language**:

- English (required)

Work Location: In person

Application Deadline: 31/08/2023
Expected Start Date: 01/11/2023



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