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Team Lead of Drug Product Development

vor 1 Monat


CorsiersurVevey, Schweiz Merck KGaA Darmstadt Germany Vollzeit

Work Your Magic with us

Ready to explore, break barriers, and discover more? We know you've got big plans - so do we Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

**Your role**:
Reporting to the Head of Early-stage Parenteral Drug Product Development in the Global Drug Product Development organization (GDPD), you have the opportunity to significantly contribute to the roll-out of high-tech CMC development laboratories in the BDC and help shape the future of biotech drug product development at Merck. You will lead a team of talented scientists who are involved in all steps of a early-stage parenteral Drug Product development, including providing support to our R&D colleagues for selection of molecules with the best developability profile. The group will be in charge of formulation development of biotech molecules entering CMC (platform and non-platform constructs, as well as ADCs), using our state-of-the-art robotic platform, and process development once a stable formulation has been identified. You will be in charge of ensuring that a robust process is developed and transferred to our GMP clinical line. You will also ensure that (pre)clinical administration studies meet the requirements to administer a newly developed drug product to animals as well as humans. Your key responsibilities in this role are to contribute to the final phases of BDC roll-out by: Collaborating with digital team and robotic / automation scientists to help setting up formulation development workflows on an end-to-end robotic system; Interacting with other leads, department head and development/analytical scientists for setting up our future formulation and process development activities; Design and coordination of formulation and process development studies, as well as (pre)clinical administration studies. Even though this is a line management position, you must be available to support the team with experimental and operational activities, when required. The Biotech Development Center (BDC) is Merck's flagship biotech investment, in line with the ambition to be the Vibrant Science and Technology Company. The BDC features cutting-edge technologies of the future with high-tech automated and digital laboratories, allowing different development functions to work together in a flexible, agile and collaborative environment. You will lead a team of 3-4 scientists with different seniority levels, and will be responsible for drug product development operations across early stages.

**Who you are**:

- MSc or PhD Graduate degree in Chemistry, Pharmacy, Biology, Biotechnology or related field, at least 2-3 years' experience in people management.
- Experience in formulation development and/or characterization of biologics (mAbs, multispecifics and ADCs), across early and late phase of development, in an industry setting;
- Experience in process development of biologics, including, but not limited to, technology transfer to clinical lines, lyophilization and material compatibility studies;
- Intermediate to advanced experience in automation and/or High Throughput Screening approaches and Data Quality principles and Quality by Design;
- Excellent in writing, interpersonal communication, and presentation in English; French is an asset

**What we offer**:We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress