Group Leader in Bispecific Antibodies

vor 3 Wochen

Schweiz Philogen Vollzeit

**Location: Zurich - Switzerland**

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**Department: Others**

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**Who we are**

Philochem AG is the R&D department of Philogen and it is located in Zurich. Philogen-Siena focuses on product optimisation/production according to GMP standards and on clinical trial investigations.

**Job description**:
**Responsibilities**:

- Isolate novel antibodies using Philochem’s phage display libraries
- Generate therapeutic prototypes for pre-clinical assessment
- Lead a group of junior scientists, including doctoral students
- Perform all laboratory work related to antibody development and contribute to the writing of technical reports
- Participate in multiple simultaneous projects
- Training and support of research associates and doctoral students
- Present scientific results internally and at international conferences

**Requirements**:

- Extensive knowledge in antibody phage display technology (experience with fully human synthetic antibody phage libraries is a plus)
- Extensive experience in cloning and expression of recombinant proteins in several expression systems (e.g., mammalian and bacterial expression)
- Excellent molecular biology skills, including ELISA, SPR, FACS, and IF
- Experience in early-stage bispecific antibodies development
- Certificate of animal experimentation in rodents (LTK Module 1 or comparable)
- Experience in conducting _in vivo_ experiments in pre-clinical models of cancer
- Excellent publication record in peer-reviewed scientific journals
- Accurate data analysis and recording to ensure full traceability (experience in R programming or similar software is a plus)
- Excellent analytical skills and good attention to detail
- Ability to work independently and in a team in a task-oriented manner
- Excellent communication and presentation skills
- Outstanding organizational and multi-tasking skills
- Strong proficiency in English is mandatory, both written and spoken

**Preferred**:

- 1-3 years of professional experience in a pharmaceutical company
- International experience and exposure to other laboratory environments
- Experience in process and project management
- Teaching skills and capable of leading a team
- Experience in clinical development, including First in human clinical dose selection

**How to apply**:

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