Phd Position On Cartilage and Osteochondral

vor 2 Monaten

Basel, Schweiz Universität Basel Vollzeit

**Your position**

The project aims to develop cartilage and osteochondral using nasal chondrocytes (cells in clinical use for repairing cartilage defects) and Melt electrowriting (MEW, i.e., an approach that combines electrospinning with 3D printing). In particular, the effect of scaffold architecture on nasal chondrocyte differentiation will be assessed. Additionally, the project aims to evaluate the regenerative capacity of the manufactured grafts in vivo (i.e., temporomandibular joint defect model in animals).
- CAD Design, material optimization, and MEW scaffold printing
- Design and conduct in vitro experiments,
- Explore the maturation of the grafts in vitro
- Generate the grafts for the animal study and analyze the regenerative tissues
- Generate scientific texts, including abstracts, publications, presentations, and protocols
- Supervision and teaching of BME / medical students

**Your profile**
- MSc in Biomedical Engineering, Material science, biotechnology, or biology or similar (required)
- Background in musculoskeletal research, cell and molecular biology, biochemistry, or tissue engineering (strong advantage)
- Experience with Biomaterial, Bioprinting and Melt Electrowriting printing (Hydrogel, Polymers, mechanical test characterization)
- Experience with cell and tissue culture, qPCR, immunoassays, viability assays, microscopy, or histology (strong advantage)
- Excitement to work in a collaborative, interdisciplinary environment
- Independent thinking, ambition, focus on discovery, and dedication to perform research of the highest quality
- Excellent communication and writing skills (English)

**We offer you**
- Opportunity to work in a high-level scientific laboratory with accomplished and new collaborators and clinical partners
- Training and guidance from experienced staff and research group leaders
- Versatile responsibilities within dynamic research groups, promoting a healthy work-life balance
- Participation to conferences and networking events with experts in Switzerland and globally
- Attractive working conditions and salary according to the standards of the University of Basel

**Application/Contact**

Apply

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