Contractor for Adme

vor 2 Wochen

Basel, Schweiz Work Selection Vollzeit

**Beschreibung**:
For our international medical partner, F. Hoffmann-La Roche Ltd. in Basel, we are looking for a qualified and motivated **Contractor for ADME - enzymology and DDI** for a temporary contract of 12 months.

**Tasks**:

- Conduct the laboratory-based assays in in vitro enzymology/DDI and allied experimental areas of small molecule drug metabolism as e.g. incubation of test substances using hepatocytes, human liver microsomes, recombinant enzymes
- Analyzing incubation samples via LC-MS/MS and radio-HPLC, including bioanalytical method development and/or validation.
- Plan, monitor, communicate and report enzymology/DDI studies both in a drug discovery and drug development setting reporting to the respective laboratory staff and supervisors
- Perform rigorous verification and develop best practices to improve the regular enzymology/DDI assays where current approaches are inadequate
- Some time may be spent in supporting the development of new enzyme phenotyping methodologies and approaches with the help of automation

**Must Haves**:

- You gained good knowledge of metabolic enzyme biochemistry (e.g. CYP450, UGT), hands-on/experimental enzyme kinetics assessment and the respective experimental designs
- Experience in bioanalytical method development/validation for radio-HPLC (e.g. Thermo®) and LC-MS/MS (e.g. Sciex®). This includes troubleshooting and data analysis (e.g.using Analyst® software)
- You have a strong interest in translational approaches leveraging in vitro data and clinical data
- Fluent English

**Nice to have**:

- Previous experience working in the pharmaceutical industry, biotech or CRO
- German skills
- Working knowledge of regulatory expectations for enzymology studies (e.g. chemical inhibition, recombinant enzyme and correlation studies) is an advantage

Wir wertschätzen Vielfalt und begrüssen daher alle Bewerbungen - unabhängig von Geschlecht, sozialer Herkunft, Religion, Alter und Identität. Zur leichteren Lesbarkeit und besseren Verständlichkeit verwenden wir nur eine Gender-Form. Selbstverständlich sind im jeweiligen Kontext alle Genderformen gleichermassen gemeint.

  • Project Planner/scheduler

    Vor 4 Tagen

    Basel, Schweiz Turner & Townsend Vollzeit

    **Company Description** At Turner & Townsend we’re passionate about making the difference. That means delivering better outcomes for our clients, helping our people to realize their potential, and doing our part to create a prosperous society. Every day we help our major Pharmaceutical clients deliver ambitious and highly technical projects worldwide. Are...

  • Project Planner/Scheduler

    Vor 2 Tagen

    Basel, Schweiz Turner & Townsend Vollzeit

    Job DescriptionThe Planner function includes advanced planning, scheduling, progress measurement & change management implementation.  A thorough understanding is required of policies, methods, and procedures that includes advanced Planning and Scheduling techniques, Risk Analysis, Risk Management, and support of project objectives. The Planner will provide...

  • Project Planner/Scheduler

    Vor 4 Tagen

    Basel, Schweiz Turner & Townsend Vollzeit

    Company Description At Turner & Townsend we’re passionate about making the difference. That means delivering better outcomes for our clients, helping our people to realize their potential, and doing our part to create a prosperous society. Every day we help our major Pharmaceutical clients deliver ambitious and highly technical projects worldwide. ...

  • Project Planner/Scheduler

    vor 4 Wochen

    Basel, Schweiz Turner & Townsend Vollzeit

    Company Description At Turner & Townsend we’re passionate about making the difference. That means delivering better outcomes for our clients, helping our people to realize their potential, and doing our part to create a prosperous society. Every day we help our major Pharmaceutical clients deliver ambitious and highly technical projects worldwide. ...

  • Junior Electrical Planner

    Vor 7 Tagen

    Basel, Schweiz Hitachi Zosen Inova Vollzeit

    **Junior Electrical Planner**: Hitachi Zosen Inova AG Zürich (Schweiz) Presence / Mobile Work experience Engineer Technical occupations (other) **About us**: - Zurich-based green-tech company Hitachi Zosen Inova (HZI) is a global leader in solutions for energy transition and circular economy including Energy from Waste (EfW) and Renewable Gas (RG),...

  • Lab Manager, Pharmaceutical Sciences

    vor 3 Wochen

    Basel, Schweiz Roche Vollzeit

    The Position In Roche’sPharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicine. Together, we create a culture defined by curiosity, responsibility...

  • Global Expert Strategic Facility Management 70-100%

    Vor 3 Tagen

    Basel, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international medical partner, F. Hoffmann-La Roche Ltd. in Basel, we are looking for a qualified and motivated** Local Cutover Lead** for a temporary contract of 12 months. Within the Diagnostic Division, the Global Capital Investment and Real Estate function, Global Expert Facility Management is responsible for strategy,...

  • Construction Manager

    vor 4 Wochen

    Basel, Schweiz PM Group Vollzeit

    **Construction Manager**: - Contract - Onsite - Basel, Switzerland - Engineering - 7326 **Overview - We have an requirement for experienced Construction Project Manager to join the PM Group. For this role, we need someone who has the capability to manage Mechanical Construction activities for large scale pharmaceutical construction project. - This is a...

  • Construction Manager

    vor 4 Wochen

    Basel, Schweiz PM Group Vollzeit

    : We have an requirement for experienced Construction Project Manager to join the PM Group. For this role, we need someone who has the capability to manage Mechanical Construction activities for large scale pharmaceutical construction project. This is a Site Based Role in Switzerland. : - Institutes a culture of safety, quality, speed, and effectiveness....

  • Global Expert Strategic Facility Management

    vor 4 Wochen

    Basel, Schweiz We make it Vollzeit

    Beschreibung: We make it GmbH is a company operating nationally in Switzerland which, thanks to many years of successful experience, has a high level of expertise in the personnel services sector. Its recruitment activities are focussed on the core areas of industry, technology, office/administration, engineering, pharmaceuticals and IT. We make it GmbH...

  • Global Expert Strategic Facility Management

    Vor 3 Tagen

    Basel, Schweiz ITech Consult Vollzeit

    **Global Expert Strategic Facility Management (M/F/d) - Project Management / Communication skills / decision making / SAP Plant maintenance / communication / English** **Project**: For our customer a big pharmaceutical company in Basel we are looking for a highly qualified Global Expert Strategic Facility Management (M/F/d). **Background**: Within the...