Doctoral (Phd) Position in Computational Biology

Vor 3 Tagen

Martigny, Schweiz Genomics & Health Informatics Vollzeit

**About Idiap**

**Job description**
The Genomics and Health Informatics group at the Idiap Research Institute in Martigny (Switzerland) is looking for a PhD student to join a project funded by the Swiss National Science Foundation on “Investigating the role of cytoplasmic intronic sequences in ALS pathogenesis”. The student will work together with a postdoc. Additional funding for consumables, computing, and to attend international conferences is available.

**About the project**
content transcriptomic data and combine these with large scale microscopy data to investigate the impact of aberrant mRNA metabolism (alternative splicing and polyadenylation) on the developmental trajectories of motor neurons and astrocytes during early ALS pathogenesis. Experimental validation of key findings (protein fluorescent microscopy, smFISH, etc) will be performed in the Human Stem Cells and Neurodegeneration Laboratory (Prof. Rickie Patani) from the Francis Crick Institute (London) through which we have access to high-quality data (iCLIP, transcriptomic, cellular imaging).

**About our group**
The Genomics and Health Informatics group develops computational models and statistical methods to interpret large-scale longitudinal data (e.g. transcriptomics, clinical, cellular imaging) to address biological questions related to human disorders. We seek to produce top notch science and foster the development of outstanding, independent scientists through nurturing mentorship and interdisciplinary, collaborative efforts. The group is an associated member of the National Center of Competence and Research (NCCR) RNA and Disease. The group is also part of the SIB Swiss Institute of Bioinformatics, offering various training possibilities as well as networking opportunities within the Swiss bioinformatics community.

For more information about our group:
**How to apply**
- Master’s degree in bioinformatics, computational biology, or a related field.
- Strong mathematical and computational skills.
- Good level in at least one programming language.
- Proactivity and excellent analytical, communication, and organizational skills.
- Ability to work both independently and within collaborative teams productively

a strong desire to directly work with experimental biologists.
- Good knowledge of English.

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