Phd in Deep Learning and Structural Biology
Vor 2 Tagen
**The project**
In the past decade, electron cryo-tomography (cryo-ET) has revolutionized the study of biological machinery. Cryo-ET allows for the direct visualization of cellular complexes with a nanometer resolution. A major obstacle in cryo-ET remains the identification of structures of interest amidst the noisy and crowded cellular environments. The research objectives of this thesis include the development and implementation of Deep Learning models for the segmentation and structural analysis of non-discrete protein assemblies in cells imaged by cryo-ET. The research will be carried out jointly in the groups of Thomas Lemmin and Wanda Kukulski of the Institute of Biochemistry and Molecular Medicine (IBMM) at the University of Bern, in Bern, Switzerland.
**The Ph.D. Position**
- Master of Science (MSc) degree
- Proficiency in computer vision or image processing
- Knowledge in Deep Learning is a plus
- Interest in cryo-ET of cells
- Good skills in oral and written English
- Ability to work independently and to plan and direct own work
- Motivation to engage in the elaboration of a PhD dissertation
- Ability to work in a team and autonomy in scheduling research steps
- Interest for teaching and tutoring students as well as availability to interact with colleagues (engage in scientific dialogue, listen and think critically)
**General terms**
The local research environment offers an international life sciences community as well as access to excellent scientific facilities, including electron microscopy and computational resources. Bern is a beautiful city which offers an excellent quality of life, proximity to the mountains and a multitude of other opportunities for recreation.
**The Application
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Bern, Schweiz Universität Bern Universität Bern Vollzeit**PhD in Deep Learning and Structural Biology**: **The project** In the past decade, electron cryo-tomography (cryo-ET) has revolutionized the study of biological machinery. Cryo-ET allows for the direct visualization of cellular complexes with a nanometer resolution. A major obstacle in cryo-ET remains the identification of structures of interest amidst the...
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