Industry Internship
Vor 2 Tagen
**Cimeio Therapeutics** is an applied gene editing, cellular, and immunotherapy company developing a portfolio of Shielded-Cell & Immunotherapy Pairs for patients with debilitating and life-threatening diseases. Cimeio’s proprietary technology platform is based on the discovery of novel protein variants, which when inserted into cells allow them to preserve function while resisting depletion by a precisely paired immunotherapy. This technology has significant therapeutic potential, which Cimeio is using to develop curative treatments for patients with genetic diseases, hematologic malignancies, and severe autoimmune disorders.
As an Intern Cell Biology you will have the possibility to gain industry experience in the fields of cell biology and gene editing.
We are a highly engaged team of scientists determined to make a difference for cutting edge medicine. We have an open, welcoming atmosphere, where everybody in the team actively contributes to the progress of our therapeutic programs.
**RESPONSIBILITIES**
- Cultivating, transfecting, and transducing mammalian cell lines to express and assess recombinant cell surface receptors
- Isolating primary human cells, e.g., T-cells and myeloid cells, for functional analyses
- Performing multi-colour flow cytometry
- Setting up functional assays using cell lines and primary human cells to assess the functional activity of immune cell surface receptors, e.g. Incucyte, ELISA, Western Blot, AlphaLisa etc.
- Conducting CRISPR/Cas based gene editing of human cell lines incl single cell sorting and generating clonal cell lines
- Supporting general laboratory duties and maintenance of relevant lab equipment
- Performing data analysis of data generated
- Writing up of experimental procedures and final analysis report(s)
**QUALIFICATIONS**
- PhD in cell biology, molecular biology, immunology, oncology, or genetics
- Extensive expertise in handling mammalian cell lines and primary immune cells is required
- Broad background in human cell biology incl flow cytometry
- Understanding of CRISPR/Cas gene editing in mammalian cells would be a plus
- Enthusiasm developing, applying, and optimizing new protocols and techniques
- Well-organized, highly motivated, and quick to learn
- Highly collaborative and able to work in an interactive and fast-paced R&D environment
- Profound knowledge of Excel, GraphPad Prism and PowerPoint; enthusiasm for structuring information as well as experience in preparing presentations and presenting work results in front of a variety of audiences
- Being able to work in multicultural environment
- Communication and presentation skills, fluency in written and spoken English are required
**WHAT WE CURRENTLY OFFER**
- **Offices**: Our well-equipped laboratories and offices are located at the Tech Park Basel, a premier address for early-stage start-ups.
- **Commuter Benefits**:We support our employees tailored to their personal needs in commuting to work and offer parking facilities or a commuter contribution.
- **Flexible Working**: We support flexible working as appropriate.
- **Christmas Closure**:In addition to the 24 holidays per year, our offices/labs are closed between Christmas and New Year.
- **Birthday Retreat**: On top of that, your birthday is your personal holiday - our employees enjoy their birthday with a day off.
- **Food**:We like get-togethers during lunch time. Enjoy tasty, subsidised meals from our FELFEL food fridge.
- **Coffee**: Meet up with your colleagues and grab free coffee.
- **Development**:We support the individual development of our employees.
- **German Lessons**: For our international employees we support German lessons to speed up integration.
- **Creativity**:We offer an innovative and creative environment.
- **People**:We are an international and diverse team with talented and passionate people.
- **Fun**: From time-to-time we organise cool off-site summer and winter team events.
**Job Type**: Internship
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