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Postdoctoral Research Fellow
vor 2 Monaten
University Children's Hospital Zurich_
**Postdoctoral Research Fellow**
**Your responsibilities**: We seek highly motivated and talented individuals to be part of the ENCOURAGER project, a collaborative effort funded by Fight Kids Cancer. Our work focuses on studying the causes of resistance to targeted therapy in pediatric gliomas. The applicant will investigate the longitudinal evolution of gliomas under treatment using pediatric glioma PDX models. The main tasks include generation and in vivo treatment of orthotopic brain tumor models, optimisation of a new protocol for single-cell ChIP-seq and generation of single-cell RNAseq data. The multi-omic single cell data analysis to characterize drug resistant populations will be performed in collaboration with Dr. Florence Cavalli's group at Institute Curie.
**Your profile**:
- A PhD in cancer, molecular or cell biology, or related fields is required, with strong knowledge and interest in cancer research / cancer cell biology
- LTK1 certification or equivalent is mandatory
- Proven productivity in cancer research
- Experience working with PDXs and other tumor models
- Experience in statistical analysis using R
- Expertise in single cell RNAseq analysis is an asset but not required
- Ability to work independently within a multidisciplinary team, strong team player
- Proficiency in English and excellent scientific writing skills
**What we offer**: The position is funded for an initial term of 2 years with a competitive salary/benefits and possibility of renewal.
**Place of work**: Balgrist Campus AG, Lengghalde, Zürich, Switzerland
**Start of employment**: The starting date is flexible, selection will start immediately and continue until the position is filled.
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