Technical Scientist/ Research Associate
vor 2 Monaten
Supporting in vitro-based characterization of first-in-class immuno-oncology drugs_
**Responsibilities include, but are not limited to**:
- Develop, optimize and conduct cell-based assays focused on characterization of T cell engagers
- Co-culture assays with primary cells/cancer cell lines
- T-cell proliferation/activation
- Cytotoxicity and cytokine induction (LDH, CTG, Incucyte)
- Execute routine immunological, molecular, and cellular assays
- Perform ELISAs, cell-based assays, isolation of nucleic acids, and qPCR
- Analyze experiments using multicolor flow cytometry
- Independently analyze and present results to a diverse scientific audience
- Maintain and optimize mammalian cell culture processes
**Qualifications**:
- Laboratory Technician/B.Sc./M.Sc. with research experience in the fields of immunology and/or cancer immunotherapy, 2+ years industry experience
- Required previous experience in conducting cell-based assays and analysis of multiple immune endpoints (cytotoxicity, proliferation, cytokine levels)
- Experience with primary cells culture preferred
- Experience with 384 wells co-culture assay setups preferred
- Experience with flow cytometry
- Use of analysis software GraphPad Prism
- Well-organized with an independent and accurate working style, ability to handle multiple tasks in parallel
- Positive, reliable, open-minded, and flexible team player with excellent communication skills
- Fluency in English
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