Research Internship

vor 3 Wochen

Bern, Schweiz Insel, Universitätsspital, Bern, Laboratory of Translational Immunometabolism Vollzeit

Tasks
- Support a clinical study (in obese children and adolesencts), preclinical study (in mice and cells)
- Gain laboaratory experience
- Patients contact (recruitment of patients, follow-up calls)
- Assistance during study visit, sample collection, preparation, and storage
- Extract DNA from the oral & faecal samples, blood sample analysis by Mass-Spectrometry
- Preparation of study products

Background

The prevalence of obesity and its associated comorbidities is rapidly increasing world-wide and imposes a huge socio-economic burden due to increased morbidity and mortality. In children (age 5-19), the prevalence of obesity has dramatically risen and affects more than **124 million children** **worldwide**. Obesity is not only a chronic disease in itself, but also a major risk factor for the world’s leading causes of poor health and early death including cardiovascular disease, several common cancers, diabetes, and osteoarthritis. Childhood obesity is often carried through into adulthood, due to both physiological and behavioural factors, and **preventing obesity** in this age group, therefore provides a unique opportunity to halt a course to unhealthy adult life. The gut **microbiota** and bacteria-derived metabolites (e.g. short-chain fatty acids, SCFA) have been described to play an important role in obesity. The loss in microbial diversity observed in obesity has been linked to metabolic alterations including changes in SCFA abundance that could be improved with **oral fibre supplementation**, such as galactooligosaccharides.

**The aim of this study is thus to assess the effect of a chewing gum containing GOS on body weight, metabolism, and the oral and intestinal microbiomes in a population of obese children.**

**Job Types**: 60-80%, 40-60%
Part-time hours: 25 per week

**Salary**: CHF5.00 per year

**Benefits**:

- Company events
- Company phone
- Employee discount
- Free drinks
- Work from home

Schedule:

- Day shift

Supplemental pay types:

- Tips

Ability to commute/relocate:

- 3010 Bern, BE: Reliably commute or planning to relocate before starting work (required)

**Education**:

- High school or equivalent (preferred)

**Language**:

- German (required)

Work Location: In person

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