P2255 - Associate Principal Scientist
Vor 2 Tagen
Description
Debiopharm is an independent biopharmaceutical company based in Switzerland with an ongoing commitment to research in oncology and infectious diseases in order to improve patient outcomes and quality of life. Our main activities include drug development, drug manufacturing and digital health investment. Debiopharm International SA aims to develop innovative therapies that target high unmet medical needs. Our unique “development only” business model allows us to act as a bridge between disruptive discovery products and patient access in international markets. We first identify high-potential compounds for in-licensing, clinically demonstrate their safety and efficacy and then select large pharmaceutical commercialization partners to maximize patient access globally.
At Debiopharm you will be at the forefront of the fight against cancer and infectious diseases, and you will have the opportunity to work on new innovative medicines for patients. Efficiency is our mode of action, saving lives our collective target.
For our Translational Medicine organization based at our Headquarters in Lausanne, we are looking for a
Associate Principal Scientist, Toxicology/Preclinical Safety
**Your responsibilities will be but not limited to**:
Perform safety profiling and participate in compounds selection, including on/off target toxicity
Provide toxicological expertise to multidisciplinary teams
Manage preclinical safety studies in Contract Research Organizations: design, monitor, discuss and report the safety findings;
Contribute to the preparation of preclinical safety regulatory documents (including IB, summaries for IND and IMPD, briefing documentation)
Perform mechanistic studies on toxicology findings
Identify early toxicology biomarkers for preclinical and clinical studies
May represent the Translational Preclinical Safety function in the Translational Medicine Project Teams and Global Project Teams;
Participate in internal and external scientific communications (oral presentations, posters, publication).
**Requirements**:
University degree in Life Science (Master or PhD in relevant expertise area or equivalent in biomedicine)
At least 4-6 years demonstrated experience in Toxicology/Preclinical Safety in drug development
Experience in the pharma industry, oncology experience is an asset
Knowledge in preclinical research, including animal and in vitro studies
Knowledge of GCP, GCLP and ICH guidelines and animal welfare regulations
Scientific rigor, organizational skills
Scientific interest, curiosity, motivation and excellent collaborative skills
Excellent communication and presentation skills (oral and written)
Ability to influence through the matrix, demonstrated assertiveness and impact in communication
Project management experience is a strong asset
Fluent in English
Good IT and analytical skills
**Benefits**:
International, highly dynamic environment with a long term vision.
Cross-functional collaboration at the forefront of the most advanced scientific developments in oncology and anti-bacterial industry
Exposure to a wide variety of areas and functions within clinical development and the pharmaceutical industry
Participation in a company where innovation, people and entrepreneurship are the fundamental keys to success.
Proud to be an Equal-Pay certified, we ensure offering to all our employees the same opportunities
Submission of unsolicited resumes in advance of an agreement between the Human Resources Department and the external staffing agency or recruiter does not create any implied obligation on the part of Debiopharm.
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