Associate Director/director, in Vivo Biology and

Vor 4 Tagen

Basel, Schweiz Monte Rosa Therapeutics, Inc Vollzeit

Overview:
Monte Rosa Therapeutics is looking for an experienced, energetic, and self-motivated scientist who will join our team in Basel or Boston to work on the discovery and characterization of novel medicines. At Monte Rosa we are taking a rational approach to targeting disease-causing proteins for degradation by delivering pioneering therapies for cancer, inflammation and rare genetic diseases. Delivering this new generation of treatments to patients requires a conceptual change. Monte Rosa recognizes this urgent need and is missioned to develop innovative molecular glue degraders (MGDs) as a solution. Our team combines deep knowledge and outstanding skills in the areas of chemistry, structural and cell biology, computational modeling and translational science to deliver pioneering degrader therapeutics for inflammatory and autoimmune diseases, hematological disorders and oncology.

This role includes both
_in vitro_ and i

**Responsibilities**:

- Participate in and oversee biology aspects of various projects within the pipeline and act as _in vitro_ and _in vivo_ Biology lead on one or more project or program team.
- Take a key role in driving team drug discovery biology efforts to support hit-to-lead selection and progression thought lead optimization, in vivo PK/PD and efficacy studies and early clinical translational strategy.
- Train bench-based team members and oversee the work of others in-house and at CROs; potential to manage direct report/s.
- Utilize literature and bioinformatics data to design and test therapeutic and biomarker hypotheses.
- Strengthen and develop _in vivo_ platform efforts and in-house _in vivo_ capabilities across the organization
- Participate collaboratively with others to identify target opportunities across the proprietary MGD platform

Qualifications:

- PhD Immunology or Cell Biology with 12-15 years hands-on experience in drug discovery research in a pharmaceutical setting.
- Broad experience with _in vitro_ and _in vivo_ immunology models and experience overseeing _in vitro_ and _in vivo_ CRO work is required.
- Multiparameter flow cytometry, immune cell assay and ex vivo immune cell analysis experience required.
- Established track record in driving projects forward, both as an individual contributor and as a cross-functional collaborator.
- Excellent interpersonal skills and ability to work in a matrixed team and adapt to rapidly changing priorities and deadlines.

  • (Associate) Director, Cancer Cell Biology

    Vor 7 Tagen

    Basel, Schweiz Ridgeline Discovery GmbH Vollzeit

    **Ridgeline Discovery is look**ing for an (Associate) Director, Cancer Cell Biology**. **Ridgeline Discovery**, a Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe. In recent years, Ridgeline has assembled an international...

  • (Associate) Director, Cancer Cell Biology

    Vor 7 Tagen

    Basel, Schweiz Ridgeline Discovery GmbH Vollzeit

    **Ridgeline Discovery is look**ing for an (Associate) Director, Cancer Cell Biology**. **Ridgeline Discovery**, a Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe. In recent years, Ridgeline has assembled an international...

  • Research Associate Ex Vivo

    vor 7 Monaten

    Basel, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international medical partner, F. Hoffmann-La Roche Ltd. in Basel, we are looking for a qualified and motivated **Research Associate ex vivo / in-vivo models in Rare Blood Disorders** for a temporary contract of 12 months with a possible extension. In the Immunology group, we are developing cutting edge therapies to treat rare...

  • Research Associate in Vivo Gene Therapy in Rare

    vor 5 Monaten

    Basel, Schweiz ITech Consult Vollzeit

    **Research Associate (M/F/d) in vivo gene therapy in Rare Blood Disorders - LTK1** **/* **in vivo experiments** **/** **ELISA / biochemical assays / English* **Project**: For our customer a big pharmaceutical company in Basel we are looking for a highly qualified **Research Associate (M/F/d) in vivo gene therapy in Rare Blood...

  • Research Associate Ex Vivo/in Vivo Models in Rare

    Vor 7 Tagen

    Basel, Schweiz We make it Vollzeit

    Beschreibung: We make it GmbH is a company operating nationally in Switzerland, which has a high level of competence in the personnel services sector thanks to many years of successful experience. Concentration of placement activities on the core areas of industry, technology, office/administration, engineering, pharmaceuticals and IT. We make it GmbH...

  • Research Associate Ex Vivo/in Vivo Models in Rare

    Vor 7 Tagen

    Basel, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international partner based in Basel, we are looking for a qualified and motivated **Research Associate ex vivo/in vivo models in Rare Blood Disorders** for a temporary contract of 12 months with option for extension. In the Immunology group, they are developing cutting edge therapies to treat rare blood disorders. As a member of...

  • Associate Director or Director Pharmacometrics

    Vor 4 Tagen

    Basel, Schweiz Hengrui USA Vollzeit

    **Reports to (Title): Head of Pharmacometrics** **Location: Basel Switzerland** **Direct Reports : No** **Department: Clinical Pharmacology & Early Development** **Job Summary**: **Essential Job Functions**: - Proficiency in PK, PK/PD, and model-informed drug development (MIDD) principles and analyses. - Serves as a modeling and simulation (M&S)...

  • Associate Director or Director of Pharmacometrics

    vor 2 Wochen

    Basel, Schweiz Hengrui Europe Therapeutics AG Vollzeit

    **Job Title**: Associate Director or Director of Pharmacometrics **Reports to (Title)**: Head of Pharmacometrics **Location**: Basel Switzerland **Direct Reports**: No **Department**: Clinical Pharmacology & Early Development **About Hengrui**: The Hengrui ex-China organization drives the development and commercialization of the Hengrui innovative...

  • Research Associate In-vivo Pharmacology

    vor 7 Monaten

    Basel, Schweiz Work Selection Vollzeit

    **Beschreibung**: For our international medical partner, F. Hoffmann-La Roche Ltd. in Basel, we are looking for a qualified and motivated **Research Associate in-vivo Pharmacology** for a temporary contract of 12 months with a possible extension. **Tasks**: - Help to refine and independently execute a mouse models used for in vivo studies related to lung...

  • Research Associate In-vivo Pharmacology

    vor 7 Monaten

    Basel, Schweiz We make it Vollzeit

    Beschreibung: We make it GmbH is a company operating nationally in Switzerland, which has a high level of competence in the personnel services sector thanks to many years of successful experience. Concentration of placement activities on the core areas of industry, technology, office/administration, engineering, pharmaceuticals and IT. We make it GmbH...

  • Research Associate In-vivo Pharmacology

    vor 7 Monaten

    Basel, Schweiz Global Personal Partner Vollzeit

    **EINFÜHRUNG**: Our profession and our passion "HR Management." Global Personal is an independent company of the Interiman Group SA with over 100 employees offering a complete range of human resources services at 21 locations in German-speaking Switzerland. For our client, an international orientated Pharma company in Basel we are looking for a reliable...

  • Research Associate Ex Vivo/in Vivo Models in Rare

    vor 7 Monaten

    Basel, Schweiz Personal Contact Basel AG Vollzeit

    Personal Contact vermittelt und verleiht seit über 25 Jahren erfolgreich qualifiziertes Personal in den Bereichen Industrie, Pharma, Technik und Gewerbe. Mit Fachkompetenz, Menschlichkeit und Engagement bietet Personal Contact lückenlose Dienstleistungen an, welche den höchsten qualitativen Ansprüchen des Personalwesens entsprechen. Für ein...

  • Research Associate in Vivo Models

    vor 7 Monaten

    Basel, Schweiz We make it GmbH Vollzeit

    We make it GmbH is a company operating nationally in Switzerland, which has a high level of competence in the personnel services sector thanks to many years of successful experience. Concentration of placement activities on the core areas of industry, technology, office/administration, engineering, pharmaceuticals and IT. We make it GmbH places the highest...

  • Co-Director, Institute of Human Biology

    Vor 3 Tagen

    Basel, Schweiz F. Hoffmann-La Roche AG Vollzeit

    Co-Director, Institute of Human BiologyCo-Director, Institute of Human BiologyApply locations Basel time type Full time posted on Posted 2 Days Ago job requisition id 202412-132677Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to...

  • Associate Director Strategy

    vor 2 Monaten

    Basel, Schweiz Abbott Laboratories Vollzeit

    **Abbott **is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 114,000 colleagues serve people in more than 160...

  • Research Associate in vivo models in Rare Blood Disorders

    vor 2 Monaten

    Basel, Schweiz F. Hoffmann-La Roche AG Vollzeit

    Research Associate in vivo models in Rare Blood DisordersThe PositionAt Roche, we believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives and we are fearless in both decision and action. And we believe that good business means a better world.In the...

  • Associate Director/director

    vor 22 Stunden

    Basel, Schweiz Novartis Vollzeit

    6000+! That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. The Oncology Research department at Novartis Institutes for Biomedical Research is...

  • Associate Director, Accounting

    vor 7 Monaten

    Basel, Schweiz CTC Resourcing Solutions Vollzeit

    For our client, an International Pharmaceutical company located in the Basel area, Switzerland, we are looking for a **Associate Director, Accounting & Consolidation** The Associate Director Accounting & Consolidation performs the **consolidation **and is **responsible for supporting quarterly reporting**. The position holder supports **bookkeeping and...

  • Research Associate In-vivo Pharmacology

    vor 7 Monaten

    Basel, Schweiz We make it GmbH Vollzeit

    We make it GmbH is a company operating nationally in Switzerland, which has a high level of competence in the personnel services sector thanks to many years of successful experience. Concentration of placement activities on the core areas of industry, technology, office/administration, engineering, pharmaceuticals and IT. We make it GmbH places the highest...

  • Business Analytics Associate Director

    vor 7 Monaten

    Basel, Schweiz Novartis Vollzeit

    390892BR **Business Analytics Associate Director**: Switzerland **About the role** Location: Basel, Switzerland (Hybrid) **About this role**: Our **Business Analytics Associate Director** manages metrics for 400+ trials, provides analytics as a service, and advance automation and data science tools to enable data driven decision making to reduce clinical...