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Pathology Research Associate F/m/d)

vor 2 Monaten

Basel, Schweiz We make it Vollzeit

Beschreibung:
We make it GmbH is a company operating nationally in Switzerland, which has a high level of competence in the personnel services sector thanks to many years of successful experience.

Concentration of placement activities on the core areas of industry, technology, office/administration, engineering, pharmaceuticals and IT. We make it GmbH places the highest demands on quality, ethics and discretion.

For our client, a renowned pharmaceutical company based in Basel, we are looking for a Pathology Research Associate (f/m/d)

**Pathology Research Associate **(f/m/d)**:
In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

You will join the Roche Institute of Translational Bioengineering (ITB), an organisation within pRED whose goal is to harness and advance the use of human model systems in drug discovery and development, as well as personalised medicine. Our interdisciplinary research bridges academic and pharmaceutical research, connecting biologists, engineers, and data scientists. We partner and collaborate with leading scientific institutions worldwide to tackle grand challenges by assembling, funding, and leading interdisciplinary teams of experts to work on highly ambitious and complex scientific questions. You will work closely with the Non-clinical Investigative Pathology team to establish and adapt innovative tissue technologies to Human model systems.

**Task and Responsibilites**
- Support the characterization of human model systems through robust and standardized pathology workflows
- Innovation of tissue based technologies applied to human model systems
- Coordinate among the ITB teams and with the PS Pathology chapter the tasks to be done and perform pathology related experiments (tissue processing, sectioning, staining, imaging, documentation)
- raining for immunostaining for ITB scientists
- Lab work includes Embedding, sectioning, staining
- Organizing protocols

**You must have these qualifications**
- A university degree, BSc or MSc, in biology or a life science discipline or an apprenticeship in biology/medical lab environment and justify a strong understanding of cell biology, physiology, and/or tissue engineering. (**)
- min. 1 year Experience with manual and automated pathology procedures: tissue processing (trimming, dehydration, embedding), sectioning (microtome/cryostat), clearing methods, immunostaining (histology, IHC, IF), in situ hybridization, scanning (brightfield and fluorescence), antigen retrieval (**)
- Ability to design, test and optimize multiplex IHC/IF stainings including on challenging samples (e.g. organoids and microfluidic chip formats) (**)
- Manual and automated quantitative image analysis (ImageJ, Imaris and/or HALO) (**)
- proficient English level (**)
- Excellent organization, documentation and interpersonal skills

**Nice to haves**
- Confocal microscopy
- Spatial phenotyping
- 3D in vitro cell culture
- Experience with histology evaluation is an asset

**Work hours**
- Fixed working hours

**Are you interested?

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