Postdoctoral Position: Development of Artificial

vor 1 Woche


Basel, Schweiz Universität Basel Vollzeit

**Your position**

The overall aim of this project is the development of a platform of artificial cells based on encapsulation of artificial organelles containing enzymes in micrometer-sized cell-like compartments. When specific molecules are present in the environment of the cell-like compartments, they serve as signals and trigger the functionality inside the artificial organelles in a similar manner as in natural cells. A particularly important part of the project will intend to produce artificial organelles and encapsulate them inside cell-like compartments. In addition, the evaluation of the enzymatic activity of the organelles before and after their encapsulation inside the artificial cells represents a prerequisite for development of such multifunctional assemblies. This platform of artificial cells will

This is an interdisciplinary project from which you will gain valuable experience in the domain of nanoscience, physical chemistry, synthetic biology and biosensing approaches. Your role will be to produce artificial organelles by encapsulation of enzymes inside compartments with nanometer size, to encapsulate them by microfluidics in micrometer-sized compartments, and to control the overall

**Your profile**
- you will ideally have a PhD in chemistry, biochemistry or biochemical engineering
- experience in producing compartments (liposomes or polymersomes) is a must
- basic knowledge of molecular biology techniques (e.g. PCR, DNA purification)
- basic knowledge of protein biochemistry techniques (e.g. gel electrophoresis, protein purification)
- experience in microfuidics technology
- high records of publications in internationally refereed scientific journals
- Swiss citizenship or of one EU country
- proficiency in English; German is an advantage

**We offer you**

The University of Basel is an Equal Opportunity Employer.

**Application / Contact**

For further information, please contact Prof. Dr. Cornelia Palivan,

i. letter of motivation
ii. curriculum vitae
iii. names and contact details for two referees


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