Scientist – Antibody

Join Our Mission to Translate Cutting-Edge Research into Life-Changing Therapeutics

We (the group of Prof. Andreas Moor at the Department of Biosystems Science and Engineering of ETH Zurich, located in Basel) are currently seeking a visionary scientist to join our team and drive antibody and nanobody-based drug discovery (start immediately or by arrangement). This position is ideal for a researcher with a background in biotechnology, molecular biology, or related fields, who is eager to transform pioneering research into practical, patient-focused solutions.

In this role, you will work at the convergence of fundamental research and translational development - advancing antibodies and nanobodies from early discovery toward therapeutic applications. Your responsibilities will include initial discovery, rigorous screening, and detailed characterization of novel protein binders aimed at disease-relevant targets, in an environment that values both scientific excellence and strategic application.

• Experimentation: Design and execute studies to develop and characterize novel antibodies and nanobodies.
• Optimization: Apply molecular biology and protein engineering techniques to enhance binders for affinity, specificity, and stability.
• Assay Development: Create and validate cell-based assays to assess therapeutic potential.
• Collaborative Innovation: Work alongside interdisciplinary teams, including clinical and industry experts, to advance discoveries from bench toward preclinical applications.
• Strategic Development: Contribute to initiatives related to technology transfer, intellectual property, and the evolution of our therapeutic pipeline.

Qualifications

• A Master's degree or PhD degree in the relevant field with a proven track record of hands-on experience in the workflows and protocols relevant for the position.
• Excellent interpersonal skills and creativity, "out of the box" thinking.
• Ability to operate under pressure and deliver results within specified timelines and budgets.

Areas of technical expertise include:

• Fluorescent microscopy, flow cytometry, cell sorting.
• ELISA and BLI assays.
• Display assays (phage, yeast, or ribosome).
• Mammalian cell culture.
• Regulatory experience or prior drug development exposure is a plus.
• Animal experimentation experience is a plus.

This role is tailored for scientists who:

• Are passionate about antibody and nanobody-based therapeutics.
• Aspire to see innovative research evolve into tangible clinical solutions.
• Value a collaborative setting where scientific inquiry meets strategic development (i.e. spinoffs, startups, and commercialization).
• Thrive in a dynamic environment that bridges discovery with practical impact.

We offer:

• Join a pioneering research team that is shaping the future of biotherapeutics.
• Gain hands-on experience in translational science and drug development.
• Collaborate in an interdisciplinary environment alongside academic and industry experts.
• Play a key role in developing intellectual property and fostering potential spinoff ventures.
• Embrace the challenge of advancing novel therapeutics from the lab to patient care.

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity, and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish.

We look forward to receiving your online application with the following documents:

• Cover letter (Which of your research projects was most exciting to you so far and why? Why would you like to join us?)
• CV
• Names of 3 references

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

Further information about the laboratory can be found on our website. For more information about the position, contact Prof. Andreas Moor (andreas.moor@bsse.ethz.ch) (no applications).

ETH Zurich is one of the world's leading universities specializing in science and technology. We are renowned for our excellent education, cutting-edge fundamental research, and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.