PostDoc position in Microbial Proteogenomics

To reinforce our team in Wädenswil, Switzerland, we are seeking aPostDoc position in Microbial Proteogenomics & Integrated Data Analysis

Job Description

Agroscope is the Swiss centre of excellence for research in agriculture, nutrition and the environment. We have an opening for a motivated PostDoc to join AS SOON AS POSSIBLE. Start date: March 1, 2025 (or upon agreement).

The Microbial Genomics & Bioinformatics team is working on various innovative research projects with renowned experimental partners. This includes a proteogenomics solution we developed for identifying new, unannotated protein-coding genes in bacterial genomes, some of which perform important functions (https://iptgxdb.expasy.org/).

Tasks

1. Extend the functionality of the proteogenomics solution (expert system to prioritize novel CDS; study synthetic communities and simple eukaryotes).
2. Identification of new proteins with relevant functions for symbiosis and biocontrol, e.g., antimicrobial peptides and effectors.
3. Application of methods such as genome assembly, genome annotation, comparative genomics, and multi-omics data integration.
4. Optimizing and applying existing analysis pipelines, e.g., for de novo genome assembly or to search large public proteomics data.
5. Publication of bioinformatics tools and results in scientific journals; contribution to the acquisition of third-party funding.

Profile Requirements

1. PhD in bioinformatics, computational biology, or similar.
2. Strong skills in analyzing and integrating functional genomics data, especially proteomics -DDA and DIA workflows- and genomics. Experience in analysis of Ribo-seq, Tn-seq data is beneficial.
3. In-depth programming experience (Python, Linux scripting/bash, R); experience in scientific publishing.
4. Interest in the further development/optimization of software solutions and making these accessible to scientific experts.
5. Knowledge of (ideally) two official Swiss languages and a very good command of written and spoken English.

For further information, please contact Dr. Christian Ahrens, Team Leader Microbial Genomics & Bioinformatics (Molecular Ecology Group, Agroscope) and Group Leader at the SIB Swiss Institute of Bioinformatics (https://www.sib.swiss/christian-ahrens-group).

How to Apply

If you are interested in this challenging and highly interesting position, please send your application including CV and letter of motivation to: christian.ahrens@agroscope.admin.ch

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