Research Associate, Preclinical Development

Vor 4 Tagen

Basel, Schweiz Matterhorn Biosciences AG Vollzeit

Ridgeline Discovery, a Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe. In recent years, Ridgeline has assembled an international team of highly experienced drug discovery and industry professionals and built and operated multiple new successful companies; these companies have raised significant funds through Series B, IPO and an exit through a trade sale.

We are looking for a highly skilled and motivated Research Associate to enhance our preclinical team and contribute to the development of innovative therapeutic modalities. This position is a one-year fixed-term opportunity that offers a tremendous chance to support our portfolio companies within an experienced, vibrant, and agile biotech team.

In this role, you will bring hands-on expertise in protein characterization and developability studies, while contributing to a dynamic and collaborative environment. The ideal candidate is a proactive and enthusiastic team player with strong analytical and organizational abilities, eager to expand their skills beyond their core expertise.

RESPONSIBILITIES

  1. Perform analytical testing of diverse therapeutic modalities to support product characterization and quality control.
  2. Design and execute developability studies, including stress tests and analytical screenings, with therapeutic development candidates.
  3. Design and perform formulation screenings, including feasibility studies for high-concentration formulations.
  4. Adapt and optimize experimental approaches based on modalities, leveraging literature research to inform study design.
  5. Develop and implement novel, state-of-the-art characterization techniques.
  6. Support outsourced preclinical studies as CRO coordinator and manage study logistics.
  7. Review, analyze, and interpret experimental data, generating clear figures and tables for presentations and technical reports.
  8. Serve as a technical expert in project team meetings, providing data-driven recommendations for candidate selection.
  9. Accurately and promptly document experimental results in electronic lab notebooks in compliance with internal standards.

QUALIFICATIONS

  1. Master’s degree in a scientific discipline with 2+ years of relevant experience in academia, biotechnology, or the pharmaceutical industry.
  2. Comprehensive understanding and practical expertise in analytical tools for protein characterization, including chromatography techniques (e.g., SEC, HIC, IEX) and electrophoretic methods (e.g., cIEF, CE-SDS).
  3. Experience in small molecule characterization and formulation is a strong plus.
  4. Prior hands-on experience with mass spectrometry is highly desirable.
  5. Demonstrated ability to maintain a high level of scientific rigor, precision, and attention to detail in experimental design and execution.

WHAT WE CURRENTLY OFFER

  1. People: We are an international and diverse team with talented and passionate people.
  2. Creativity: We offer an innovative and creative environment.
  3. Development: We support the individual development of our employees.
  4. Fun: From time to time we organize cool off-site summer and winter team events.
  5. Offices: Our well-equipped laboratories and offices are located at the Tech Park, a premier address for early-stage start-ups in Basel.
  6. Commuter Benefits: We support our employees tailored to their personal needs in commuting to work and offer parking facilities or a commuter contribution.
  7. Flexible Working: We support flexible working as appropriate.
  8. Christmas Closure: In addition to the 24 holidays per year, our offices/labs are closed between Christmas and New Year.
  9. Birthday Retreat: On top of that, your birthday is your personal holiday - our employees enjoy their birthday with a day off.
  10. Food: We like get-togethers during lunch time. Enjoy tasty, subsidised meals from our FELFEL food fridge.
  11. Coffee: Meet up with your colleagues and grab free coffee.

To apply, please submit your completed application form along with your CV, cover letter, and reference letters (Arbeitszeugnisse).

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