Postdoctoral Position
Vor 3 Tagen
IntroductionPostdoctoral Position – DeepMarrow collaborative TANDEM project @Laboratory of Regenerative Hematopoiesis (GR-NAVEIRAS). A newly funded ISREC Foundation TANDEM project is in search of a highly motivated postdoc to bring together clinicians, engineers and computational biologists to develop, train and apply an artificial intelligence-based digital histopathology workflow named DeepMarrow to contribute to outcome stratification in acute myeloid leukemia (AML). The team is based in Lausanne, Switzerland, and encompasses three institutions: (i) the University of Lausanne (UNIL) Faculty of Biology and Medicine, a leading public institution of higher education and research in Switzerland, (ii) the Lausanne University Hospital, repeatedly ranked as one of the 20 best academic hospitals in the world, and (iii) the École Polytechnique Fédérale de Lausanne, one of the world’s most prestigious engineering, technology and science institutions. The collaborating laboratories are part of the Swiss Cancer Center Leman network (https://sccl.ch/).Presentationco-led by Prof. Olaia Naveiras (Department of Biomedical Sciences, UNIL) and the Hematology Service Translational Research Unit, and by Dr. Daniel Sage at the EPFL Biomedical Imaging Group. The project focuses on the study of unexplored morphological features and spatial relationships in bone marrow tissue sections from patients undergoing induction chemotherapy for AML, with benchmarking against other scenarios of intense bone marrow remodeling. Key contributing collaborators to the project are Prof. Laurence de Leval (Institute of Pathology, CHUVUNIL), Prof. Bart Deplancke (Institute of Bio-engineering, EPFL) and Prof. Sabine Blum (Service of Hematology, CHUV).Job informationExpected start date: 01.03.2026 or subject to work visa approvalContract length: 24 months (12+12 months, with possibility of a 3rd year)Activity rate: 80-100%Workplace: Lausanne, UNIL-FBM (CHUV Bugnon campus)Your responsibilitiesWe are looking for a rigorous, creative, and team-driven individual with a passion for and ideally already substantial expertise in image analysis and related machine learning approaches and a desire for clinical impact. The selected candidate will collaborate closely with clinicians to securely structure the longitudinal bone marrow image cohort and coded clinical data associated to the three currently approved local, national and international cohorts, while developing the DeepMarrow workflow and morphological feature extraction from the available training set (doi: 10.1016/j.modpat.2022.100088) and identifying specific samples for multimodal discovery analysis (multiplex immunohistochemistry and spatial transcriptomics). Guaranteed in-depth exposure to machine learning, advanced hematopathology, multimodal omics analyses including spatial transcriptomics and marrow stromal niche biology within a highly motivated and collaborative team.Your qualificationsPhD or MD/PhD degree in computational biology or pathology, preferably in the fields of cancer or stem cell biologyHighly autonomous in computational analysis, skilled in image and/or transcriptomic data processing, and able to manage projects that integrate data curation and deep learning workflowsWet-lab expertise in cell biology or experimental pathology (e.g. morphological tissue assessment, H&E, immunohistochemistry, primary human tissue processing) is a mustPrior experience in obtaining ethical approval and handling of human primary tissues, including knowledge of the legal and ethical framework (e.g. TRREE certification) will be highly valuedExpertise in diagnostic hematopathology or experimental hematology will be highly valuedDemonstrated capacity for project management in a highly collaborative setting is a mustFluency in English with outstanding oral and written communication skillsPreference will be given to outstanding candidates with a solid record of peer-reviewed publications and/or selective international conference presentations available to start in March-April 2026.What the position offers youA dynamic, stimulating, interdisciplinary research environment, state-of-the-art technologies, cuttingedge core facilities, and attractive employment conditions in addition to fascinating life in Switzerland. The UNIL/CHUV medical campus and the EPFL campus are in Lausanne, in close proximity from Lake Geneva and the Swiss Alps.Contact for further informationProf. Olaia Naveiras and Dr. Daniel Sage Email (all three please): E-Mail schreiben, E-Mail schreiben, E-Mail schreiben Subject line : TANDEM DeepMarrow position.Your applicationApplications should include a motivation letter, complete CV and at least two reference letters (including a letter from the PhD advisor, unless duly justified).Selected candidates will be contacted by mid January for interviews on Thursday January 22nd.Please send your full application in PDF format. Deadline for applications: January 2nd 2026.Selected candidates will be contacted and invited for interviews on January 2026.Only applications through this website and addressed to all three emails and with the specified subject line will be considered.Additional informationequality, diversity and inclusion within its community; ensuring an open and respectful environment that is conducive to personal development; offering working conditions that facilitate work-life balance; supporting early career researchers.unil.ch/equality unil.ch/families unil.ch/graduatecampus #J-18808-Ljbffr
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