Head of CADD

Vor 6 Tagen

Basel, Basel-Stadt, Schweiz Novartis Farmacéutica Vollzeit
Head of CADD (Computer-Aided Drug Discovery)

Job ID REQ-10034233

Summary

Over 20 million
That's the number of proprietary quantitative activity measurements available for data mining and modeling. Imagine leading a team at the forefront of drug discovery, where you can leverage this vast knowledge base, along with proprietary structural and pharmacological target information, to uncover groundbreaking drug candidates. As the head of the Computer-Aided Drug Discovery (CADD) team in Basel, Switzerland, you'll delve into cutting-edge science and technology, such as generative chemistry and high-performance computing, within a collaborative, multidisciplinary environment.

Join our vibrant team at Basel GDC and be at the forefront of drug discovery and technological innovation We're on the lookout for a unique and seasoned computational scientist to lead our dynamic team, which thrives on interdisciplinary collaboration and boasts both local and global impact.

About the Role

Major accountabilities:

Step into a pivotal role where your expertise will guide groundbreaking research programs within the BR portfolio. As a visionary leader, you will:

  • Initiate and steer research programs, setting ambitious long-term goals and ensuring their successful completion across multiple projects.
  • Drive our digital transformation, be part of our ambitious AI/ML strategy to bring computational methods to the forefront of drug discovery.
  • Apply your hands-on experience in advanced modeling and dynamics simulations to unravel the 3D structural mechanisms of novel ligands, in collaboration with experimental scientists.
  • Influence drug discovery with your expertise in generative and computational-first approaches, driving projects from inception to fruition.
  • Lead interdisciplinary teams in making informed decisions, from target identification to candidate nomination, with your strategic insights.
  • Pioneer new practices to address complex challenges, setting a benchmark for scientific problem-solving.
  • Shape the med chem portfolio's strategy, overseeing its progression from early to late stages and guaranteeing impactful outcomes.
  • Foster scientific excellence by integrating cutting-edge technologies that enhance research productivity.
  • Direct scientific endeavors across sites as a key member of the Global CADD leadership team, advocating for novel technologies and representing CADD and GDC both internally and externally.
  • Mentor and nurture talent, providing guidance to direct reports and selected scientists, aligning their development with their experience and focus areas.
  • Offer strategic counsel to local and global teams, addressing management and performance issues with your seasoned perspective.
  • Stay at the forefront of science, engaging with the scientific community to incorporate the latest insights into computational drug discovery approaches.

We are looking for someone with:

  • Possess an advanced degree in computational chemistry, biology, chemical biology, or a related field.
  • Have over a decade of experience in applying computational methods to drug discovery.
  • Demonstrate a proven record of delivering disease candidates to the clinic.
  • Exhibit a strong record of creating successful strategies and delivering digital transformations.
  • Showcase hands-on expertise with significant impact in various CADD approaches, including Structure-based Drug Design, AI/ML and Computational-first approaches, Virtual Screening, Hit and Lead Finding, Molecular Dynamics, Free Energy Calculations, Multi-Objective Optimization, and Generative Chemistry.
  • Maintain a strong presence in the scientific community, evidenced by peer-reviewed publications and presentations at prestigious venues.
  • Receive leadership recognition for strategic direction, project initiation, overcoming obstacles, advancing science, and contributing to the drug discovery pipeline.
  • Proven experience in managing and nurturing the growth of scientists.

We invite you to bring your wealth of knowledge and leadership to our team, where your contributions will be pivotal in advancing the frontiers of medicine.

Why Novartis? Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us

Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Accessibility & Accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

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