Postdoc - Advanced Process Control

Vor 3 Tagen

Schaffhausen, Schaffhausen, Schweiz J&J Family of Companies Vollzeit

Postdoc - Advanced Process Control W

Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at .

We are seeking a highly motivated and skilled Postdoctoral Scientist to join our team and participate in an exciting automated control project in the field of continuous manufacturing of biologics. The successful candidate will contribute to developing and implementing automation strategies in a biologics drug products setting, with a focus on modeling and process control.

They will work closely with the Schaffhausen pilot plant innovation and the global process science modeling & data teams to demonstrate the value of PAT (Process Analytical Technology) and modeling for real-time process monitoring and control.

Help us build the next generation of fill finish plant

Responsibilities:

  • Design and implement an automation solution to enable the efficient, flexible, and accurate mixing and filling of parenteral drug product (DP) in a continuous manufacturing setup.
  • Build a (simplified) process model that can be used in, e.g., a model predictive control setup, to optimize the control policy in real time under hard and soft constraints.
  • Work together with other modelers focusing on detailed multi-physics descriptions to ensure the model used as part of the control strategy accurately gathers the relevant quality and performance metrics.
  • Collaborate with different departments to integrate the various available sensors into the automation system and estimate the system states. Work together to fix emerging issues and ensure smooth operations.

Qualifications

  • PhD in an engineering field (e.g., chemical, process, mechanical, electrical). Past exposure to continuous manufacturing in a pharmaceutical setting is a plus.
  • Proficiency in modeling and simulation of unit operations in tools such as python, Matlab or gPROMS.
  • A strong background in process automation and control, including state estimation techniques. Familiarity with PAT tools and sensors and with orchestrators such as synTQ or SIPAT.
  • Excellent problem-solving abilities, able to identify and address potential issues proactively and independently.
  • Strong communication and teamwork skills, with the ability to work effectively in a multi-functional team environment.

For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world's most pressing healthcare challenges.

We know that the success of our business – and our ability to deliver meaningful solutions – depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.

At Johnson & Johnson, we all belong.

Primary Location Europe/Middle East/Africa-Switzerland-Schaffhausen-Schaffhausen

Organization Cilag AG (8562)

Job Function Post Doc & Data Analytics & Computational Sciences

Req ID: W


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