Dsp/enzyme Scientist

vor 1 Woche

Schlieren, Zürich, Schweiz Anjarium Biosciences AG Vollzeit

Anjarium is a privately held, early-stage biotechnology company focused on creating a new class of non-viral gene therapies to deliver more predictable, enduring, and inclusionary ways to tackle genetic disease throughout a patient's lifetime.

The Company's versatile platform aims to leverage breakthrough science and expertise at the interface of genetic medicine, synthetic biology and nanoparticle engineering to generate a pipeline of advanced gene therapies with unique competitive advantages over current viral-vector based gene therapies.

We are backed by leading international and strategic investors Abingworth, Gimv, Omega Funds, Pfizer Ventures and Surveyor Capital (a Citadel company).


Currently headquartered at Biotechnopark in Zurich, Switzerland, we are rapidly expanding our teamand are looking for talented and creative individuals, driven by patient outcomes, to join us.

Our team is passionate about building a new generation of durable genetic medicines for life-threatening diseases while pushing forward the frontiers of gene therapy.


Key Responsibilities:

  • Investigate purification procedures for proteins and nucleic acids by chromatography and other DSPrelevant techniques
  • Develop and execute assays to improve our understanding of enzyme function and focus enzyme improvement efforts
  • Investigate implementation of analytical procedures to assess quality and quantity of purified products
  • Work independently and as part of a collaborative team to design, plan, and execute experiments to facilitate in vitro and in vivo evaluation of nucleic acid batches
  • Proper documentation of experiments and data into an electronic laboratory journal

Qualifications and Experience:

  • Master Degree or higher in a relevant field with 1 to 4 years of industrial experience
  • Track record of engineering or improving proteins using structural biology or directed evolution approaches
  • Demonstrated ability to develop biochemical assays
  • Experience with downstream process development using DoE, ideally with handson experience on DSP unit operations like IEX chromatography and UF/DF
  • Handson experience with preparative chromatography systems (like Äkta systems)
  • Good understanding of quality criteria related to DSP of proteins and nucleic acids
  • Strong written and verbal communicator in English
  • High personal standards with requirements in return for their working environment such as transparency, respect and caring communication

Key Interpersonal Skills:

  • Driven by curiosity and eagerness to learn more every day
  • Strong desire to be impactful
  • High personal standards with requirements in return for their working environment such as transparency, respect and caring communication
  • Submission of unsolicited resumes in advance of an agreement between Anjarium and any external staffing agency or recruiter does not create any implied obligation on the part of Anjarium Biosciences AG. _

  • Director - Head Process Development

    vor 3 Wochen

    Schlieren, Schweiz Anjarium Biosciences AG Vollzeit

    Anjarium is a privately held, early-stage biotechnology company focused on creating a new class of non-viral gene therapies to deliver more predictable, enduring, and inclusionary ways to tackle genetic disease throughout a patient’s lifetime. The Company’s versatile platform aims to leverage breakthrough science and expertise at the interface of genetic...