Phd Student Position in Topic Molecular

vor 1 Woche


Bern, Bern, Schweiz Universität Bern Vollzeit

PhD student position:
Find possible mechanisms and new markers of adrenarche, a prepubertal event of human sexual development

100%, starting date or later


The aim of the SNF-funded project "AdmiR3" is to understand fundamental mechanisms regulating human adrenarche, a critical prepubertal event in human sexual development.

With multi-omics approaches we will investigate human biomaterials and perform cellbased studies in order to understand underlying mechanisms of regulation of this event in health and disease.

Tasks

  • Generation and analysis of transcriptome profiles to investigate the impact of small and messenger RNAs in human
adrenarche

  • Use of multiple animal models to interrogate the conservation of hypothesisdriven mechanisms of adrenarche
across species

  • Chemical and genetic manipulation in human cell models of androgen biosynthesis, including reprogrammed
iPSCs, for investigating the fine molecular mechanisms of adrenarche

  • Support and preparation of scientific reports and journal articles

Requirements:

  • Master's degree in (Bio)Physics, (Bio)engineering, Biological Sciences,
  • Microbiology, Biochemistry, Systems Biology, Molecular Biology, Bioinformatics/Computational Biology, or related
fields

  • Experience with basic wet laboratory techniques
  • Handson experience with key biochemical and molecular biological methods
  • Motivation to work in an international research environment
  • Strong motivation to learn and commitment to science
  • Good communication skills
We offer

  • You will follow a highly recognized PhD training program at the GCB of the University of Bern
  • You will have access to stateoftheart research equipment in metabolomics, cell biology and bioinformatics
  • You will work in a dynamic and interdisciplinary team
  • You will be involved in crossdisciplinary collaborations and have training opportunities to further develop and grow
your scientific interests

  • Opportunity to work in close contact with other basic
- and clinical-researchers within the Flück/Pandey groups at

the Department of Biomedicine Research and the Department of Pediatrics

  • Support from experienced team members
A) a cover/motivation letter

B) a complete curriculum vitae
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